ArticleGenes & development2008
PERspective on PER phosphorylation.
Article in Genes & development, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- Oligomerization of PER2 as a dynamic mode of regulation of the mammalian circadian clock.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Glucocorticoid receptor regulates protein chaperone, circadian clock and affective disorder genes in the zebrafish brain.Disease models & mechanisms · 2023Article
- Article
- TOC1 clock protein phosphorylation controls complex formation with NF-YB/C to repress hypocotyl growth.The EMBO journal · 2021Article
- Time-of-day dependent effects of contractile activity on the phase of the skeletal muscle clock.The Journal of physiology · 2020Article
- Identification of pathways that regulate circadian rhythms using a larval zebrafish small molecule screen.Scientific reports · 2019Article
- Design Principles of Phosphorylation-Dependent Timekeeping in Eukaryotic Circadian Clocks.Cold Spring Harbor perspectives in biology · 2018Review
- Codon usage affects the structure and function of the Drosophila circadian clock protein PERIOD.Genes & development · 2016Article
- Non-24-Hour Sleep-Wake Disorder Revisited - A Case Study.Frontiers in neurology · 2016Article
- Circadian rhythms. Decoupling circadian clock protein turnover from circadian period determination.Science (New York, N.Y.) · 2015Article
- Turnover of protein phosphorylation evolving under stabilizing selection.Frontiers in genetics · 2014Review
- AMP-activated protein kinase as a key molecular link between metabolism and clockwork.Experimental & molecular medicine · 2013Review
- Picrotoxin dramatically speeds the mammalian circadian clock independent of Cys-loop receptors.Journal of neurophysiology · 2013Article
- Of switches and hourglasses: regulation of subcellular traffic in circadian clocks by phosphorylation.EMBO reports · 2010Article
- PRR5 regulates phosphorylation, nuclear import and subnuclear localization of TOC1 in the Arabidopsis circadian clock.The EMBO journal · 2010Article
- Essential roles of CKIdelta and CKIepsilon in the mammalian circadian clock.Proceedings of the National Academy of Sciences of the United States of America · 2009Article
- Casein kinase 1 delta regulates the pace of the mammalian circadian clock.Molecular and cellular biology · 2009Article
- The implications of multiple circadian clock origins.PLoS biology · 2009Review
- PER3 polymorphism and cardiac autonomic control: effects of sleep debt and circadian phase.American journal of physiology. Heart and circulatory physiology · 2008Article
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1 author.
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Abstract
Period (PER) proteins are essential parts of the molecular clocks that control circadian rhythms in flies and mammals. Phosphorylation regulates PER's stability and subcellular localization; however, the physiologically relevant sites have been difficult to identify in spite of knowing the relevant kinase. In this issue of Genes & Development, Chiu and colleagues (1758-1772) identify a key phosphorylation site on PER that recruits the F-box protein Slimb to trigger PER degradation and set clock speed.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.