ArticleInternational wound journal2008
What are the most effective interventions in preventing diabetic foot ulcers?
Article in International wound journal, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 109 citations in OpenAlex.
- Prognostic models for predicting the risk of foot ulcer or amputation in people with type 2 diabetes: a systematic review and external validation study.Diabetologia · 2021Pooled it
- Trial
- Proximal Midfoot Amputation as a Functional Alternative to Major Amputation in Advanced Diabetic Foot Infection: A Case Report.Journal of orthopaedic case reports · 2026Article
- Mönckeberg's Medial Calcific Sclerosis Makes Traditional Arterial Doppler's Unreliable in High-Risk Patients with Diabetes.The international journal of lower extremity wounds · 2026Article
- Article
- Recurrence rates after healing in patients with neuroischemic diabetic foot ulcers healed with and without sucrose octasulfate-impregnated dressings: A 1-year comparative prospective study.International wound journal · 2024Article
- The effects of the use of customized silicone digital orthoses on pre-ulcerative lesions and plantar pressure during walking in people with diabetic neuropathy: A study protocol for a randomized controlled trial.Contemporary clinical trials communications · 2024Article
- The correlation between Diabetes and age-related degeneration and the static and dynamic 3D mechanical distribution of different plantar regions.Frontiers in endocrinology · 2024Article
- A Scoping Review of Footwear Worn by People With Diabetes in Low- and Middle-Income Countries: Implications for Ulcer Prevention Programs.Global health, science and practice · 2023Article
- Management of diabetic foot ulcers and the challenging points: An endocrine view.World journal of diabetes · 2022Review
- Reversing painful and non-painful diabetic neuropathy with the capsaicin 8% patch: Clinical evidence for pain relief and restoration of functionFrontiers in neurology · 2022Article
- Oxygen-Releasing Composites: A Promising Approach in the Management of Diabetic Foot Ulcers.Polymers · 2021Review
- Development of a Smartphone-Based Optical Device to Measure Hemoglobin Concentration Changes for Remote Monitoring of Wounds.Biosensors · 2021Article
- Modeling, Fabrication and Integration of Wearable Smart Sensors in a Monitoring Platform for Diabetic Patients.Sensors (Basel, Switzerland) · 2021Article
- Factors Associated with Callus Formation in the Plantar Region through Gait Measurement in Patients with Diabetic Neuropathy: An Observational Case-Control Study.Sensors (Basel, Switzerland) · 2020Article
- Index of Plantar Pressure Alters with Prolonged Diabetes Duration.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019Article
- Evaluation of the use of therapeutic footwear in people with diabetes mellitus - a scoping review.Journal of diabetes and metabolic disorders · 2019Article
- Acceleration of Diabetic Wound Healing with PHD2- and miR-210-Targeting Oligonucleotides.Tissue engineering. Part A · 2019Article
- Continuous Temperature-Monitoring Socks for Home Use in Patients With Diabetes: Observational Study.Journal of medical Internet research · 2018Observational
- Multidisciplinary Approach to PAD: Who's on Your Team?Seminars in interventional radiology · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although many studies have shown strong associations between certain causal factors and patients with foot ulcers, it is unclear how many of these factors interact. A model that could help identify unique causal pathways and pivotal factors associated with the development of foot ulcers may lead to earlier intervention as well as less frequent and less severe complications. Therefore, the purpose of this study was to identify the responsible causal pathways associated with foot ulcers in persons with diabetes, to determine the frequency of components of the pathway and to identify pivotal events of the pathway. Eighty-seven patients with 103 existing or recently healed ulcers were prospectively evaluated. The data used in the pathway analysis reflected seven variables that have been associated with the development of foot ulcers. The data were interpreted to assess which component causes and pivotal events were responsible for the present ulcer. A cluster analysis was used to confirm findings from the descriptive analysis. Twenty-four pathways were identified. The seven most common unique pathways accounted for 64.1% of the cases. The results of the cluster analysis showed four consistent, dominant clusters: (i) neuropathy, deformity, callus and elevated peak pressure; (ii) peripheral vascular disease; (iii) penetrating trauma and (iv) Ill-fitting shoe gear. These results suggest that there is a finite number of key factors that, if identified and addressed with appropriate intervention strategies, may reduce the risk for the cascade of events towards ulceration and subsequent amputation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.