Evidence map›Paper›PMID 18592209›Full record

ArticleDiabetologia2008

Establishing glycaemic control with continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes: experience of the PedPump Study in 17 countries.

T Danne, T Battelino, P Jarosz-Chobot, O Kordonouri, E Pánkowska, J Ludvigsson, E Schober, E Kaprio, T Saukkonen, M Nicolino and 25 more

Open access · bronzeAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Diabetologia, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it, 139 citations in OpenAlex.

  1. Guideline
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. Supporting the Use of a Person's Own Diabetes Technology in the Inpatient Setting.Diabetes spectrum : a publication of the American Diabetes Association · 2022
    Article
  9. Article
  10. Review
  11. Clinical Use of Degludec in Children and Adolescents with T1D: A Narrative Review with Fictionalized Case Reports.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2019
    Review
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
  17. Review
  18. Psychological support for children with diabetes: are the guidelines being met?Journal of clinical psychology in medical settings · 2014
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 20 institutions in 21 countries.

T DanneKinderkrankenhaus auf der Bult, Hanover, Janusz-Korczak-Allee 12, 30173 Hanover, Germany. danne@hka.de
T Battelino
P Jarosz-Chobot
O Kordonouri
E Pánkowska
J Ludvigsson
E Schober
E Kaprio
T Saukkonen
M Nicolino
N Tubiana-Rufi
C Klinkert
H Haberland
A Vazeou
L Madacsy
D Zangen
V Cherubini
I Rabbone
S Toni
C de Beaufort
W Bakker-van Waarde
N van den Berg
I Volkov
R Barrio
R Hanas
U Zumsteg
B Kuhlmann
C Aebi
U Schumacher
S Gschwend
P Hindmarsh
M Torres
N Shehadeh
M Phillip
PedPump Study Group
Boston Children's Hospital · USHeart and Diabetes Center North Rhine-Westphalia · DELinköping University · SEMedical University of Silesia · PLPeijas Hospital · FIRussian Children's Clinical Hospital · RUSchneider Children's Medical Center · ILSemmelweis University · HUUniversity Medical Center Groningen · NLZug Cantonal Hospital · CHCentre Hospitalier de Luxembourg · LUDiabetes UK · GBHadassah Medical Center · ILHelsinki Children's Hospital · FIHôpital Debrousse · FRKantonsspital Münsterlingen · CHKinderkrankenhaus auf der Bult · DEMarche Polytechnic University · ITMedical University of Warsaw · PLMeyer (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aims/hypothesisTo assess the use of paediatric continuous subcutaneous infusion (CSII) under real-life conditions by analysing data recorded for up to 90 days and relating them to outcome.

methodsPump programming data from patients aged 0-18 years treated with CSII in 30 centres from 16 European countries and Israel were recorded during routine clinical visits. HbA(1c) was measured centrally.

resultsA total of 1,041 patients (age: 11.8 +/- 4.2 years; diabetes duration: 6.0 +/- 3.6 years; average CSII duration: 2.0 +/- 1.3 years; HbA(1c): 8.0 +/- 1.3% [means +/- SD]) participated. Glycaemic control was better in preschool (n = 142; 7.5 +/- 0.9%) and pre-adolescent (6-11 years, n = 321; 7.7 +/- 1.0%) children than in adolescent patients (12-18 years, n = 578; 8.3 +/- 1.4%). There was a significant negative correlation between HbA(1c) and daily bolus number, but not between HbA(1c) and total daily insulin dose. The use of <6.7 daily boluses was a significant predictor of an HbA(1c) level >7.5%. The incidence of severe hypoglycaemia and ketoacidosis was 6.63 and 6.26 events per 100 patient-years, respectively. CONCLUSIONS/

interpretationThis large paediatric survey of CSII shows that glycaemic targets can be frequently achieved, particularly in young children, and the incidence of acute complications is low. Adequate substitution of basal and prandial insulin is associated with a better HbA(1c).

Indexed as

Insulin Infusion SystemsAdolescentBlood GlucoseChildCross-Sectional StudiesDiabetes Mellitus, Type 1Drug Administration ScheduleEuropeGlycated HemoglobinHumansInjections, SubcutaneousInsulinRetrospective StudiesBlood GlucoseGlycated HemoglobinInsulin

Identifiers

PMID18592209
OpenAlexW2134440063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.