Evidence map›Paper›PMID 18588980›Full record

ReviewPharmacological research2008

Immune system in renal injury and repair: burning the candle from both ends?

Michael S Goligorsky

Open access · greenAbstract readReview
In one paragraph

Review in Pharmacological research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Small Leucine-Rich Proteoglycans in Renal Inflammation: Two Sides of the Coin.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2018
    Review
  4. Danger-Associated Molecular Patterns Derived From the Extracellular Matrix Provide Temporal Control of Innate Immunity.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2018
    Review
  5. Article
  6. Dangers within: DAMP responses to damage and cell death in kidney disease.Journal of the American Society of Nephrology : JASN · 2011
    Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Michael S GoligorskyRenal Research Institute and Division of Nephrology, Department of Medicine and Pharmacology, New York Medical College, Valhalla, NY 10595, United States. michael_goligorsky@nymc.edu
Renal Research Institute · US

Funding

RENAL ENDOTHELIAL AND SMOOTH MUSCLE CELLS INTERACTIONSR01DK045462 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI GOLIGORSKY, MICHAEL S · 1995 to 2014
$4.8M
VASCULAR PERMEABILITY IN DIABETIC NEPHROPATHYR01DK054602 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI GOLIGORSKY, MICHAEL S · 1999 to 2010
$2.5M
Endothelial dysfunction in acute renal ischemiaR01DK052783 · NIDDK · STATE UNIVERSITY NEW YORK STONY BROOK · PI GOLIGORSKY, MICHAEL S · 1997 to 2007
$2.0M
NIDDK NIH HHS DK052783NIDDK NIH HHS DK054602NIDDK NIH HHS DK45462NIDDK NIH HHS R01 DK045462NIDDK NIH HHS R01 DK052783NIDDK NIH HHS R01 DK054602
6 · The paper itself

Abstract

This brief overview is focused on the inherent duality of immune responses: on the one hand they may induce inflammation and precipitate injury, on the other, a number of examples of participation in organ and tissue repair are growing. These processes will be reviewed from the nephrological stand-point. Specifically, the role of different leukocyte subsets, innate immunity, nitric oxide production, and stem cells, among others, are presented.

Indexed as

AnimalsEndothelial CellsHematopoietic Stem Cell MobilizationHumansImmune SystemImmunity, InnateKidneyKidney DiseasesMesenchymal Stem Cell TransplantationNitric OxideRegenerationToll-Like ReceptorsNitric OxideToll-Like Receptors

Identifiers

PMID18588980
PMCPMC2755216
OpenAlexW2052699016

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.