Evidence map›Paper›PMID 18587552›Full record

ReviewDer Urologe. Ausg. A2008

[Value of targeted treatment for testicular cancer: from molecular approaches to clinical possibilities].

A Martinschek, C G Ruf, C Sparwasser, H U Schmelz

Abstract readEnglish AbstractReview
PubMed Publisher
In one paragraph

Review in Der Urologe. Ausg. A, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

A MartinschekAbteilung Urologie, Bundeswehrkrankenhaus, Oberer Eselsberg 40, 89081 Ulm, Deutschland. Martinschek@web.de
C G Ruf
C Sparwasser
H U Schmelz
Bundeswehrkrankenhaus · DEBundeswehrkrankenhaus · DEBundeswehrzentralkrankenhaus Koblenz · DEUniversität der Bundeswehr München · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the introduction of tyrosine kinase-inhibitors in the treatment of metastatic renal cell cancer, targeted therapy raises hopes for other urological tumors as well. Even if excellent cure rates, achieved by standardization of diagnosis und therapy, have made testicular cancer a curable disease, up to 6% of young patients still die from tumors refractory to therapy. The quality of life of patients in advanced stages needing aggressive treatment should be improved by new therapies with reduced side effects. The role of tyrosine kinase inhibitors and angiogenesis inhibitors as well as intervention in the cell cycle and induction of apoptosis are discussed.

Indexed as

Drug Delivery SystemsAngiogenesis InhibitorsAntineoplastic AgentsCell CycleCell MovementCell ProliferationDNA Mutational AnalysisGene ExpressionGene Expression Regulation, NeoplasticGenetic TherapyGene Transfer TechniquesHumansMaleProtein-Tyrosine KinasesTesticular NeoplasmsAngiogenesis InhibitorsAntineoplastic AgentsProtein-Tyrosine Kinases

Identifiers

PMID18587552
OpenAlexW1493978594

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.