Evidence map›Paper›PMID 18587534›Full record

ArticleJournal of neuro-oncology2008

Gamma knife radiosurgery for treatment resistant choroid plexus papillomas.

In-Young Kim, Ajay Niranjan, Douglas Kondziolka, John C Flickinger, L Dade Lunsford

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of neuro-oncology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Giant cystic choroid plexus papilloma mimicking intracerebral hydatid cyst.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Clinical outcome of pediatric choroid plexus tumors: retrospective analysis from a single institute.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2014
    Article
  8. Review
  9. A novel TP53 somatic mutation involved in the pathogenesis of pediatric choroid plexus carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2012
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

In-Young KimDepartment of Neurological Surgery, Center for Image-Guided Neurosurgery, Medical Center-Presbyterian, University of Pittsburgh, 200 Lothrop Street, Suite B-400, Pittsburgh, PA 15213, USA.
Ajay Niranjan
Douglas Kondziolka
John C Flickinger
L Dade Lunsford
University of Pittsburgh · USChonnam National University · KRNeurological Surgery · USUPMC Presbyterian · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo report the results of gamma knife radiosurgery (GKR) for treatment resistant choroid plexus papillomas.

methodsSix patients (median age 55 years; range 29-75) with residual (n = 2) or recurrent (n = 4) choroid plexus papillomas underwent GKR. All failed prior surgery and one failed prior proton beam radiation therapy. These six patients had a total of 11 locally or distant recurrent intracranial tumors. The median and mean tumor volumes were 2.7 and 3.9 cc (range, 0.23-21.1). A median margin dose of 12.0 Gy (range, 11.5-15) was prescribed to the tumor margin.

resultsThe progression-free periods varied from 7 to 108 months (mean: 36.9). Four tumors were stable after GKR but seven showed progression. Four recurrent tumors in two patients were managed with repeat radiosurgery and three were observed. At the second GKR, the tumor volume varied from 1.3 to 12.4 cc, and the marginal radiation dose varied from 11 to 14 Gy. The overall survival after the first GKR varied from 15 to 120 months. Four patients were alive at the end of the study period.

conclusionsRadiosurgery represents an additional management strategy for patients who progress despite surgical removal. It may especially be useful for patients with small deep seated residual choroid plexus papillomas, and for tumors that recur at a site distant from their origin.

Indexed as

AdultAgedBrain NeoplasmsDisease-Free SurvivalFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNeoplasm Recurrence, LocalPapilloma, Choroid PlexusRadiosurgery

Identifiers

PMID18587534
OpenAlexW2067689583

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.