Evidence map›Paper›PMID 18587440›Full record

GuidelineBone marrow transplantation2008

Management of CMV, HHV-6, HHV-7 and Kaposi-sarcoma herpesvirus (HHV-8) infections in patients with hematological malignancies and after SCT.

P Ljungman, R de la Camara, C Cordonnier, H Einsele, D Engelhard, P Reusser, J Styczynski, K Ward, European Conference on Infections in Leukemia

Registry-linked trialAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Bone marrow transplantation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02083731 (Mesenchymal Stem Cells for Treatment of CMV Infection After Hematopoietic Stem Cell Transplant), which is not on this map. Cited by 85 papers.

0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
10.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02083731 phase2unknown statusnot on this mapstarted 2014, after this paper: background citation

Mesenchymal Stem Cells for Treatment of CMV Infection After Hematopoietic Stem Cell Transplant

TypeinterventionalSponsorNanfang Hospital, Southern Medical UniversityRan2014 to 2017Enrolled120ConditionsStem Cell Transplantation, Hematopoietic, CMV Infection, Hematological DiseasesArmsMSCs
3 · Its place in the literature

Who cites it

85 citing papers in PubMed, 287 citations in OpenAlex.

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  7. Human herpesvirus 6 infection after hematopoietic cell transplantation: is routine surveillance necessary?Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2011
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  9. Review
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  18. Observational
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25 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

P LjungmanDepartment of Hematology, Karolinska University Hospital/Huddinge, Stockholm, Sweden. Per.Ljungman@ki.se
R de la Camara
C Cordonnier
H Einsele
D Engelhard
P Reusser
J Styczynski
K Ward
European Conference on Infections in Leukemia
Karolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

These recommendations were prepared by the European Conference on Infections in Leukaemia following a predefined methodology. Literature searches were made to identify studies pertinent to management of CMV, HHV-6, -7 and -8 infections. For CMV, 76 studies were reviewed: 72 published and 4 presented as abstracts. Twenty-nine of these studies were prospective randomized trials. For the other herpesviruses, HHV-6, -7 and -8, no randomized controlled trial has been performed, although data from some studies with other primary endpoints have been used to assess the management of HHV-6 infection. Works presented only as abstracts were used to a very limited extent. The quality of evidence and level of recommendation were graded according to the Center for Disease Control (CDC) criteria.

Indexed as

Herpesvirus 6, HumanHerpesvirus 7, HumanHerpesvirus 8, HumanStem Cell TransplantationCytomegalovirus InfectionsHematologic NeoplasmsRoseolovirus InfectionsSarcoma, Kaposi

Identifiers

PMID18587440
OpenAlexW1992168621

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.