Evidence map›Paper›PMID 18586909›Full record

ReviewDiabetes2008

Protein kinase C function in muscle, liver, and beta-cells and its therapeutic implications for type 2 diabetes.

Carsten Schmitz-Peiffer, Trevor J Biden

Open access · bronzeAbstract readReview
In one paragraph

Review in Diabetes, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
76citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

76 citing papers in PubMed, 1 synthesis or guideline pooled it, 158 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Article
  5. Insulin Resistance and Inflammation.International journal of molecular sciences · 2026
    Review
  6. Review
  7. Triglycerides, Glucose Metabolism, and Type 2 Diabetes.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Positive Effects of Physical Activity on Insulin Signaling.Current issues in molecular biology · 2024
    Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

16 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Carsten Schmitz-PeifferGarvan Institute of Medical Research, Darlinghurst, Australia.
Trevor J Biden
Garvan Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Insulin ResistanceAdaptor Proteins, Signal TransducingAnimalsCalciumDiabetes Mellitus, Type 2DiglyceridesEnzyme ActivationHumansInsulinInsulin Receptor Substrate ProteinsInsulin-Secreting CellsInsulin SecretionLiverMiceMice, KnockoutMice, TransgenicAdaptor Proteins, Signal TransducingCalciumDiglyceridesInsulinInsulin Receptor Substrate ProteinsIRS1 protein, humanIrs1 protein, mouseProtein Kinase C

Identifiers

PMID18586909
PMCPMC2453608
OpenAlexW2121990555

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.