ArticleJournal of neurology, neurosurgery, and psychiatry2008
Predictive value of the Essen Stroke Risk Score and Ankle Brachial Index in acute ischaemic stroke patients from 85 German stroke units.
Article in Journal of neurology, neurosurgery, and psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 2 of them syntheses that pooled it.
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Who cites it
26 citing papers in PubMed, 2 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- Comparison between clopidogrel and ticagrelor in CYP2C19 loss-of-function alleles coronary artery disease and stroke patients: a meta-analysis.European journal of clinical pharmacology · 2025Pooled it
- Pooled it
- Matrix Gla protein polymorphism rs1800801 associates with recurrence of ischemic stroke.PloS one · 2020Trial
- Association Between Ankle-Brachial Index and Risk of Early Neurological Deterioration After Acute Isolated Pontine Infarction.Brain and behavior · 2025Article
- Serum Angiopoietin-Like Protein 4 as a Biomarker for Acute Ischemic Stroke Severity and Dynamic Changes.Brain and behavior · 2025Article
- Ankle-Brachial Index as a Predictor of Acute Ischemic Cerebrovascular Event After Central Retinal Artery Occlusion.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Evaluation of Triglyceride Glucose Index in Patients with Patent Foramen Ovale Who Experienced Cryptogenic Stroke.Journal of clinical medicine · 2024Article
- Clinical study of the prognostic value of the Essen score for acute cerebral infarction.Irish journal of medical science · 2024Article
- Association of plaque characteristics with long-term stroke recurrence in patients with intracranial atherosclerotic disease: a 3D high-resolution MRI-based cohort study.European radiology · 2024Article
- Ticagrelor Aspirin vs Clopidogrel Aspirin inNeurology · 2023Article
- Carotid plaque score and ischemic stroke risk stratification through a combination of B-mode and contrast-enhanced ultrasound in patients with low and intermediate carotid stenosis.Frontiers in cardiovascular medicine · 2023Article
- The Predictive Value of Essen and SPI-II on the Risk of 5-Year Recurrence in Chinese Patients with Acute Ischemic Stroke.Neuropsychiatric disease and treatment · 2023Article
- Association between CHADSJournal of clinical medicine · 2022Article
- Delayed massive cerebral infarction after perioperative period of anterior cervical discectomy and fusion: A case report.World journal of clinical cases · 2021Article
- Risk of recurrent stroke and antiplatelet choice in breakthrough stroke while on aspirin.Scientific reports · 2020Article
- Article
- Clinical Risk Score for Predicting Recurrence Following a Cerebral Ischemic Event.Frontiers in neurology · 2019Review
- CHAJournal of thrombosis and thrombolysis · 2018Article
- Article
- CHAMayo Clinic proceedings · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundRisk stratification can contribute to individualised optimal secondary prevention in patients with cerebrovascular disease.
objectiveTo prospectively investigate the prediction of the Essen Stroke Risk Score (ESRS) and a pathological Ankle Brachial Index (ABI) in consecutive patients hospitalised with acute ischaemic stroke or transient ischaemic attack (TIA) in 85 neurological stroke units throughout Germany.
methods852 patients were prospectively documented on standardised case report forms, including assessment of ESRS and ABI. After 17.5 months, recurrent cerebrovascular events, functional outcome or death could be assessed in 729 patients predominantly via central telephone interview.
resultsAfter discharge from the documenting hospital, recurrent stroke occurred in 41 patients (5.6%) and recurrent TIA in 15 patients (2.1%). 52 patients (7.1%) had died, 33 (4.5%) from cardiovascular causes. Patients with an ESRS > or = 3 (vs <3) had a significantly higher risk of recurrent stroke or cardiovascular death (9.7% vs 5.1%; odds ratio (OR) 2.00, 95% confidence interval (CI) 1.08 to 3.70) and a higher recurrent stroke risk (6.9% vs 3.7%; OR 1.93, 95% CI 0.95 to 3.94). Patients with an ABI < or = 0.9 (vs > 0.9) had a significantly higher risk of recurrent stroke or cardiovascular death (10.4% vs 5.5%; OR 2.00, 95% CI 1.12 to 3.56) and a higher recurrent stroke risk (6.6% vs 4.6%; OR 1.47, 95% CI 0.76 to 2.83).
conclusionOur prospective follow-up study shows a significantly higher rate of recurrent stroke or cardiovascular death and a clear trend for a higher rate of recurrent stroke in patients with acute cerebrovascular events classified as high risk by an ESRS > or = 3 or a pathological ABI.
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Registered trials
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