ArticleNature genetics2008
Conflicting evidence on the frequency of ESR1 amplification in breast cancer.
Article in Nature genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- Novel Treatment Strategies for Hormone Receptor (HR)-Positive, HER2-Negative Metastatic Breast Cancer.Journal of clinical medicine · 2024Review
- Frequent ESR1 and CDK Pathway Copy-Number Alterations in Metastatic Breast Cancer.Molecular cancer research : MCR · 2019Article
- Review
- Amplification of HER2 and TOP2A and deletion of TOP2A genes in a series of Taiwanese breast cancer.Medicine · 2017Article
- Estrogen receptor alpha gene amplification in breast cancer: 25 years of debate.World journal of clinical oncology · 2016Review
- ESR1 gene status correlates with estrogen receptor protein levels measured by ligand binding assay and immunohistochemistry.Molecular oncology · 2012Article
- Oncogene amplification in male breast cancer: analysis by multiplex ligation-dependent probe amplification.Breast cancer research and treatment · 2012Article
- Prognostic and predictive role of ESR1 status for postmenopausal patients with endocrine-responsive early breast cancer in the Danish cohort of the BIG 1-98 trial.Annals of oncology : official journal of the European Society for Medical Oncology · 2012Article
- The growth response to androgen receptor signaling in ERα-negative human breast cells is dependent on p21 and mediated by MAPK activation.Breast cancer research : BCR · 2012Article
- Androgen receptor as a targeted therapy for breast cancer.American journal of cancer research · 2012Article
- Significance of estrogen receptor 1 (ESR-1) gene imbalances in colon and hepatocellular carcinomas based on tissue microarrays analysis.Medical oncology (Northwood, London, England) · 2011Article
- ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study.Cellular oncology (Dordrecht, Netherlands) · 2011Article
- Current research topics in endocrine therapy for breast cancer.International journal of clinical oncology · 2008Review
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
18583976What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.