ArticleNature genetics2008
ESR1 gene amplification in breast cancer: a common phenomenon?
Article in Nature genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed.
- Estrogen Receptor Alpha Gene Amplification Is an Independent Predictor of Long-Term Outcome in Postmenopausal Patients with Endocrine-Responsive Early Breast Cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2022Trial
- Influence of DNA copy number and mRNA levels on the expression of breast cancer related proteins.Molecular oncology · 2013Trial
- Recapitulation of patient-specific 3D chromatin conformation using machine learning.Cell reports methods · 2023Article
- Mutant p53Cancers · 2021Article
- Genetic determinants of the molecular portraits of epithelial cancers.Nature communications · 2019Article
- Resistance to endocrine therapy in breast cancer: molecular mechanisms and future goals.Breast cancer research and treatment · 2019Review
- Frequent ESR1 and CDK Pathway Copy-Number Alterations in Metastatic Breast Cancer.Molecular cancer research : MCR · 2019Article
- Article
- Noncoding somatic and inherited single-nucleotide variants converge to promote ESR1 expression in breast cancer.Nature genetics · 2016Article
- Estrogen receptor alpha gene amplification in breast cancer: 25 years of debate.World journal of clinical oncology · 2016Review
- Mechanisms of aromatase inhibitor resistance.Nature reviews. Cancer · 2015Review
- Absence of estrogen receptor alpha (ESR1) gene amplification in a series of breast cancers in Taiwan.Virchows Archiv : an international journal of pathology · 2014Article
- Prognostic significance of ESR1 amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 polymorphisms in breast cancer patients.PloS one · 2013Article
- Article
- ESR1 gene status correlates with estrogen receptor protein levels measured by ligand binding assay and immunohistochemistry.Molecular oncology · 2012Article
- Prognostic and predictive role of ESR1 status for postmenopausal patients with endocrine-responsive early breast cancer in the Danish cohort of the BIG 1-98 trial.Annals of oncology : official journal of the European Society for Medical Oncology · 2012Article
- Androgen receptor as a targeted therapy for breast cancer.American journal of cancer research · 2012Article
- ESR1 gene amplification: another mechanism regulating the cellular levels of ERα.Nature reviews. Cancer · 2011Article
- ESR1 amplification is rare in breast cancer and is associated with high grade and high proliferation: a multiplex ligation-dependent probe amplification study.Cellular oncology (Dordrecht, Netherlands) · 2011Article
- Biological reprogramming in acquired resistance to endocrine therapy of breast cancer.Oncogene · 2010Article
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
18583965What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.