Evidence map›Paper›PMID 18582978›Full record

ArticleVirus research2008

RNA transcription analysis and completion of the genome sequence of yellow head nidovirus.

Nusra Sittidilokratna, Sirintip Dangtip, Jeff A Cowley, Peter J Walker

Abstract read
In one paragraph

Article in Virus research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 65 citations in OpenAlex.

  1. Review
  2. Giant RNA genomes: Roles of host, translation elongation, genome architecture, and proteome in nidoviruses.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Classification, replication, and transcription ofFrontiers in microbiology · 2023
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Review
  11. Review
  12. Article
  13. Successful yellow head virus infection ofAquaculture (Amsterdam, Netherlands) · 2015
    Article
  14. Article
  15. Article
  16. Review
  17. Shrimp molecular responses to viral pathogens.Marine biotechnology (New York, N.Y.) · 2011
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Nusra SittidilokratnaNational Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency, Phathumthani 12120, Thailand.
Sirintip Dangtip
Jeff A Cowley
Peter J Walker
Australian Centre for Disease Preparedness · AUCommonwealth Scientific and Industrial Research Organisation · AUMahidol University · THNational Center for Genetic Engineering and Biotechnology · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Yellow head virus (YHV) is a pathogen of the black tiger shrimp (Penaeus monodon) and, with gill-associated virus (GAV), is one of two known invertebrate nidoviruses. We describe sequences of the large replicase gene (ORF1a) and 5'- and 3'-terminal UTRs, completing the 26,662 nt sequence of the YHV genome. ORF1a (12,219 nt) encodes a approximately 462,662 Da polypeptide containing a putative 3C-like protease and a putative papain-like protease with the canonical C/H catalytic dyad and alpha+beta fold. The read-through pp1ab polyprotein contains putative uridylate-specific endoribonuclease and ribose-2'-O-methyl transferase domains, and an exonuclease domain incorporating unusual dual Zn2+-binding fingers. Upstream of ORF1a, the 71 nt 5'-UTR shares 82.4% identity with the 68 nt 5'-UTR of GAV. The 677 nt 3'-terminal region contains a single 60 nt ORF, commencing 298 nt downstream of ORF3, that is identical to N-terminal coding region of the 249 nt GAV ORF4. Northern blots using RNA from YHV-infected shrimp and probes directed at ORF1a, ORF1b, ORF2 and ORF3 identified a nested set of 3'-coterminal RNAs comprising the full-length genomic RNA and two sub-genomic (sg) mRNAs. Intergenic sequences upstream of ORF2 and ORF3 share high identity with GAV, particularly in the conserved domains predicted to mediate sgmRNA transcription.

Indexed as

Genome, ViralTranscription, Genetic3' Untranslated Regions5' Untranslated RegionsAmino Acid MotifsAmino Acid SequenceAnimalsBase SequenceGene Expression ProfilingMolecular Sequence DataOpen Reading FramesPenaeidaeProtein Structure, TertiaryRNA-Dependent RNA PolymeraseRNA, ViralRoniviridae3' Untranslated Regions5' Untranslated RegionsRNA-Dependent RNA PolymeraseRNA, ViralViral Proteins

Identifiers

PMID18582978
PMCPMC7114370
OpenAlexW2069490820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.