ArticleBMC neurology2008
Prediction of the survival and functional ability of severe stroke patients after ICU therapeutic intervention.
Article in BMC neurology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The effect of diabetes on mortality in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2011Pooled it
- Effects of Add-On Icosapent Ethyl With Standard Treatment on Functional Outcomes and Inflammatory Biomarkers in Acute Ischemic Stroke: A Blinded Randomized Controlled Trial.Annals of clinical and translational neurology · 2026Article
- Anxiety and depression one year after the first stroke among Lebanese survivors: proportions, changes, and predictors.BMC psychiatry · 2025Article
- Outcomes of patients admitted to the ICU for acute stroke: a retrospective cohort.BMC anesthesiology · 2022Article
- Acute ischemic stroke in a university hospital intensive care unit: 1-year costs and outcome.Acta anaesthesiologica Scandinavica · 2022Article
- The epidemiology of stroke in the Middle East.European stroke journal · 2016Review
- Predicting recovery of voluntary upper extremity movement in subacute stroke patients with severe upper extremity paresis.PloS one · 2015Article
- Characteristics and outcome of stroke patients with cerebrovascular accident at the intensive care unit of a tertiary hospital in Nigeria.Journal of the West African College of Surgeons · 2013Article
- Predicting hospital mortality using APACHE II scores in neurocritically ill patients: a prospective study.Journal of neurology · 2009Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThis study evaluated the benefits and impact of ICU therapeutic interventions on the survival and functional ability of severe cerebrovascular accident (CVA) patients.
methodsSixty-two ICU patients suffering from severe ischemic/haemorrhagic stroke were evaluated for CVA severity using APACHE II and the Glasgow coma scale (GCS). Survival was determined using Kaplan-Meier survival tables and survival prediction factors were determined by Cox multivariate analysis. Functional ability was assessed using the stroke impact scale (SIS-16) and Karnofsky score. Risk factors, life support techniques and neurosurgical interventions were recorded. One year post-CVA dependency was investigated using multivariate analysis based on linear regression.
resultsThe study cohort constituted 6% of all CVA (37.8% haemorrhagic/62.2% ischemic) admissions. Patient mean(SD) age was 65.8(12.3) years with a 1:1 male: female ratio. During the study period 16 patients had died within the ICU and seven in the year following hospital release. The mean(SD) APACHE II score at hospital admission was 14.9(6.0) and ICU mean duration of stay was 11.2(15.4) days. Mechanical ventilation was required in 37.1% of cases. Risk ratios were; GCS at admission 0.8(0.14), (p = 0.024), APACHE II 1.11(0.11), (p = 0.05) and duration of mechanical ventilation 1.07(0.07), (p = 0.046). Linear coefficients were: type of CVA - haemorrhagic versus ischemic: -18.95(4.58) (p = 0.007), GCS at hospital admission: -6.83(1.08), (p = 0.001), and duration of hospital stay -0.38(0.14), (p = 0.40).
conclusionTo ensure a better prognosis CVA patients require ICU therapeutic interventions. However, as we have shown, where tests can determine the worst affected patients with a poor vital and functional outcome should treatment be withheld?
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