ReviewDrugs & aging2008
Drug-induced urinary incontinence.
Review in Drugs & aging, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05702567 (The Effectiveness of Transvaginal Radiofrequency and Pelvic Floor Muscle Training Compared to Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence), which is not on this map. Cited by 33 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effectiveness of Transvaginal Radiofrequency and Pelvic Floor Muscle Training Compared to Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence: a Double-blind Randomized Controlled Trial
Who cites it
33 citing papers in PubMed, 1 synthesis or guideline pooled it, 95 citations in OpenAlex.
- Systematic review and meta-analysis identify significant relationships between clinical anxiety and lower urinary tract symptoms.Brain and behavior · 2021Pooled it
- PANTHERA "Pelvic Floor Disorders in Patients Under ANtineoplastic THERApy" Prospective Evaluation of Subjectively Perceived Pelvic Floor Function in Patients with Gynecologic and Breast Cancers Undergoing Systemic Antineoplastic Therapy Using a Validated Pelvic Floor Questionnaire.International urogynecology journal · 2026Observational
- Dose-dependent relationships in potential prescribing cascades: a cohort study using community pharmacy dispensing data.International journal of clinical pharmacy · 2026Article
- Drug-induced urinary incontinence in pediatric patients: A disproportionality analysis of the FDA Adverse Event Reporting System.Medicine · 2026Article
- Pharmacovigilance evidence of drug induced urinary incontinence in the FDA adverse event reporting system.Scientific reports · 2025Article
- Loop diuretics and subsequent use of urinary symptom medications in older adults: evaluation of a possible prescribing cascade.The journals of gerontology. Series A, Biological sciences and medical sciences · 2025Article
- From Evidence to Practice: A Comprehensive Analysis of Side Effects in Synthetic Anti-Depressant Therapy.Current drug safety · 2025Review
- Correlation of Self-Efficacy for Pelvic Floor Muscle Exercise with Symptoms of Stress Urinary Incontinence in Women.International urogynecology journal · 2024Article
- The prevalence of probable overactive bladder and associated risk factors among medical students in Jordan: a cross-sectional study.BMC urology · 2024Article
- A Delphi Exploration of Toileting Activity Performance in Individuals With Cerebral Palsy Within the ICF-CY Framework: Unveiling Influential Factors.Occupational therapy international · 2024Article
- Optimising the management of children with concomitant bladder dysfunction and behavioural disorders.European child & adolescent psychiatry · 2023Review
- Lower Urinary Tract Disorders as Adverse Drug Reactions-A Literature Review.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Personalised 3D-Printed Mucoadhesive Gastroretentive Hydrophilic Matrices for Managing Overactive Bladder (OAB).Pharmaceuticals (Basel, Switzerland) · 2023Article
- Urinary incontinence and related quality of life among elderly women in Tabas, South Khorasan, Iran.BMC urology · 2022Article
- Predictors of improvement in urinary incontinence in the postacute setting: A Canadian cohort study.Neurourology and urodynamics · 2022Article
- Females with Eating Disorders and Urinary Incontinence: A Psychoanalytic Perspective.International journal of environmental research and public health · 2022Article
- Urinary incontinence as a possible signal of neuromuscular toxicity during immune checkpoint inhibitor treatment: Case report and retrospective pharmacovigilance study.Frontiers in oncology · 2022Article
- Antiepileptic Drugs-Induced Enuresis in Children: An Overview.The Journal of pharmacy technology : jPT : official publication of the Association of Pharmacy Technicians · 2021Article
- Drug related problems in clinical practice: a cross-sectional study on their prevalence, risk factors and associated pharmaceutical interventions.Scientific reports · 2021Article
- Urinary incontinence associated with anxiety and depression: the impact of psychotropic drugs in a cross-sectional study from the Norwegian HUNT study.BMC psychiatry · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Physiological urinary continence depends on many factors that are potentially vulnerable to adverse drug effects, which may lead to incontinence. In principle, drugs could cause incontinence by lowering bladder outlet resistance and/or by increasing intravesical pressure, which disrupts the normal pressure relationship between the bladder and urethra and leads to urinary leakage; other possibilities include disturbances of central nervous control of voiding or an overproduction of urine. While many drug groups could theoretically induce urinary incontinence based upon pathophysiological considerations, evidence demonstrating a cause-effect relationship between drug usage and incontinence is sparse. Drug classes in which induction of incontinence has been proposed include alpha(1)-adrenoceptor antagonists, antipsychotics, benzodiazepines, antidepressants and hormone replacement therapy in postmenopausal women. However, other drug classes are not innocent in terms of causing urinary incontinence and physicians are well advised to closely monitor patients for the occurrence of incontinence after new prescriptions and/or major dosage changes.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.