ArticleMagnetic resonance in medicine2008
MR tracking of transplanted cells with "positive contrast" using manganese oxide nanoparticles.
Article in Magnetic resonance in medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 1 of them a synthesis that pooled it.
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Who cites it
65 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Manganese-derived biomaterials for tumor diagnosis and therapy.Journal of nanobiotechnology · 2024Pooled it
- Engineering the Colloidal Properties of Iron Oxide Nanoparticles for HighACS applied nano materials · 2025Article
- Using Manganese-Enhanced MRI to visualize Magnetogenetic-based Neuromodulation.bioRxiv : the preprint server for biology · 2025Article
- Manganese Oxide Nanoparticles for MRI-Based Multimodal Imaging and Theranostics.Molecules (Basel, Switzerland) · 2024Review
- Plant mediated biosynthesis of MnHeliyon · 2024Article
- A primer onFrontiers in medicine · 2023Review
- Advanced Magnetic Resonance Imaging (MRI) Techniques: Technical Principles and Applications in Nanomedicine.Cancers · 2022Review
- Multimodal Magnetic Resonance and Photoacoustic Imaging of Tumor-Specific Enzyme-Responsive Hybrid Nanoparticles for Oxygen Modulation.Frontiers in bioengineering and biotechnology · 2022Article
- Rapid Magneto-Sonoporation of Adipose-Derived Cells.Materials (Basel, Switzerland) · 2021Article
- Benefits and Detriments of Gadolinium from Medical Advances to Health and Ecological Risks.Molecules (Basel, Switzerland) · 2020Review
- New Vision for Visual Prostheses.Frontiers in neuroscience · 2020Review
- Manganese dioxide nanoparticles protect cartilage from inflammation-induced oxidative stress.Biomaterials · 2019Article
- Metal Oxide Nanoparticles in Therapeutic Regulation of Macrophage Functions.Nanomaterials (Basel, Switzerland) · 2019Review
- Functional nanoparticles for magnetic resonance imaging.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2016Review
- Tracking and Quantification of Magnetically Labeled Stem Cells using Magnetic Resonance Imaging.Advanced functional materials · 2016Article
- Siloxane Nanoprobes for Labeling and Dual Modality Functional Imaging of Neural Stem Cells.Annals of biomedical engineering · 2016Article
- DNA-gadolinium-gold nanoparticles for in vivo T1 MR imaging of transplanted human neural stem cells.Biomaterials · 2016Article
- Quantitative [Fe]MRI of PSMA-targeted SPIONs specifically discriminates among prostate tumor cell types based on their PSMA expression levels.International journal of nanomedicine · 2016Article
- Novel Preparation Methods of (52)Mn for ImmunoPET Imaging.Bioconjugate chemistry · 2015Article
- Nanoparticles and clinically applicable cell tracking.The British journal of radiology · 2015Review
5 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Rat glioma cells were labeled using electroporation with either manganese oxide (MnO) or superparamagnetic iron oxide (SPIO) nanoparticles. The viability and proliferation of SPIO-labeled cells (1.9 mg Fe/ml) or cells electroporated with a low dose of MnO (100 microg Mn/ml) was not significantly different from unlabeled cells; a higher MnO dose (785 microg Mn/ml) was found to be toxic. The cellular ion content was 0.1-0.3 pg Mn/cell and 4.4 pg Fe/cell, respectively, with cellular relaxivities of 2.5-4.8 s(-1) (R(1)) and 45-84 s(-1) (R(2)) for MnO-labeled cells. Labeled cells (SPIO and low-dose MnO) were each transplanted in contralateral brain hemispheres of rats and imaged in vivo at 9.4T. While SPIO-labeled cells produced a strong "negative contrast" due to the increase in R(2), MnO-labeled cells produced "positive contrast" with an increased R(1). Simultaneous imaging of both transplants with opposite contrast offers a method for MR "double labeling" of different cell populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.