Evidence map›Paper›PMID 18580541›Full record

GuidelineMenopause (New York, N.Y.)

Estrogen and progestogen use in postmenopausal women: July 2008 position statement of The North American Menopause Society.

Wulf H Utian, David F Archer, Gloria A Bachmann, Christopher Gallagher, Francine n Grodstein, Julia R Heiman, Victor W Henderson, Howard N Hodis, Richard H Karas, Rogerio A Lobo and 5 more

Registry-linked trialOpen access · greenAbstract readPractice Guideline
In one paragraph

Guideline in Menopause (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04228757 (A Clinical Study Assessing Efficacy of an Herbal Blend on Menopausal Symptoms and Quality of Life), which is not on this map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
32.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04228757 naunknown statusnot on this map

A Clinical Study Assessing Efficacy of an Herbal Blend on Menopausal Symptoms and Quality of Life

TypeinterventionalSponsori-Health, Inc.Ran2019 to 2020Enrolled130ConditionsMenopauseArmsphytoestrogen herbal blend, Placebo
3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 370 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. Trial
  6. Baseline serum estradiol and fracture reduction during treatment with hormone therapy: the Women's Health Initiative randomized trial.Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010
    Trial
  7. A randomized trial of the effect of estrogen and testosterone on economic behavior.Proceedings of the National Academy of Sciences of the United States of America · 2009
    Trial
  8. Trial
  9. Article
  10. Review
  11. Review
  12. Prevalence of Age-Related Sensorineural Hearing Loss and Related Factors in Elderly Patients Attending Tertiary Hospital in Tanzania.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Wulf H Utian
David F Archer
Gloria A Bachmann
Christopher Gallagher
Francine n Grodstein
Julia R Heiman
Victor W Henderson
Howard N Hodis
Richard H Karas
Rogerio A Lobo
JoAnn E Manson
Robert L Reid
Peter J Schmidt
Cynthia A Stuenkel
North American Menopause Society

Funding

Psychobiology And Treatment Of Perimenopausal Mood DisordersZIAMH002537 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI SCHMIDT, PETER · 2009 to 2025
$14.9M
PSYCHOBIOLOGY AND TREATMENT OF PERIMENOPAUSAL MOOD DISORDERSZ01MH002537 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI SCHMIDT, PETER J · 1990 to 2008
$1.7M
Intramural NIH HHS Z01 MH002537
6 · The paper itself

Abstract

objective: To update for both clinicians and the lay public the evidence-based position statement published by The North American Menopause Society (NAMS) in March 2007 regarding its recommendations for menopausal hormone therapy (HT) for postmenopausal women, with consideration for the therapeutic benefit-risk ratio at various times through menopause and beyond.

design: An Advisory Panel of clinicians and researchers expert in the field of women's health was enlisted to review the March 2007 NAMS position statement, evaluate new evidence through an evidence-based analysis, and reach consensus on recommendations. The Panel's recommendations were reviewed and approved by the NAMS Board of Trustees as an official NAMS position statement. The document was provided to other interested organizations to seek their endorsement.

results: Current evidence supports a consensus regarding the role of HT in postmenopausal women, when potential therapeutic benefits and risks around the time of menopause are considered. This paper lists all these areas along with explanatory comments. Conclusions that vary from the 2007 position statement are highlighted. Addenda include a discussion of risk concepts, a new component not included in the 2007 paper, and a recommended list of areas for future HT research. A suggested reading list of key references is also provided.

conclusions: Recent data support the initiation of HT around the time of menopause to treat menopause-related symptoms; to treat or reduce the risk of certain disorders, such as osteoporosis or fractures in select postmenopausal women; or both. The benefit-risk ratio for menopausal HT is favorable close to menopause but decreases with aging and with time since menopause in previously untreated women.

Indexed as

Estrogen Replacement TherapyPostmenopauseContraindicationsFemaleHumans

Identifiers

PMID18580541
PMCPMC2756246
OpenAlexW1573651362

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.