Evidence map›Paper›PMID 18573927›Full record

ArticleAntimicrobial agents and chemotherapy2008

Reduced biocide susceptibility in Candida albicans biofilms.

Jeniel E Nett, Kristie M Guite, Alex Ringeisen, Kathleen A Holoyda, David R Andes

Abstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Disinfectant tolerance ofMicrobiology spectrum · 2026
    Article
  2. Article
  3. Antimicrobial agents and chemotherapy · 2022
    Article
  4. Combination Therapy to Treat Fungal Biofilm-Based Infections.International journal of molecular sciences · 2020
    Review
  5. Contributions of the Biofilm Matrix toJournal of fungi (Basel, Switzerland) · 2020
    Review
  6. Article
  7. Frontiers in microbiology · 2018
    Review
  8. Plasticity of Candida albicans Biofilms.Microbiology and molecular biology reviews : MMBR · 2016
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Biofilms reduce solar disinfection of Cryptosporidium parvum oocysts.Applied and environmental microbiology · 2012
    Article
  19. Effect of usnic acid on Candida orthopsilosis and C. parapsilosis.Antimicrobial agents and chemotherapy · 2012
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jeniel E NettDepartments of Medicine, Cellular and Molecular Biology, University of Wisconsin, Madison, Wisconsin 53792, USA.
Kristie M Guite
Alex Ringeisen
Kathleen A Holoyda
David R Andes

Funding

RESEARCH TRAINING IN HEMATOLOGYT32HL007899 · NHLBI · UNIVERSITY OF WISCONSIN-MADISON · PI Jane Ellen Churpek · 1998 to 2026
$8.2M
NHLBI NIH HHS T32 HL007899NHLBI NIH HHS T32HL007899
6 · The paper itself

Abstract

Candida biofilm formation is common during infection and environmental growth. We tested the impacts of three biocides (ethanol [EtOH], H(2)O(2), and sodium dodecyl sulfate) on Candida albicans, C. parapsilosis, and C. glabrata biofilms. Higher concentrations of the biocides were required for efficacy against biofilms than for efficacy against planktonic controls. A combination study with two biocides (EtOH and H(2)O(2)) and fluconazole demonstrated that the combination had enhanced efficacy.

Indexed as

Antifungal AgentsBiofilmsCandidaCandida albicansCandida glabrataDisinfectantsDrug InteractionsDrug Resistance, FungalDrug Therapy, CombinationEthanolFluconazoleHumansHydrogen PeroxideMicrobial Sensitivity TestsSodium Dodecyl SulfateAntifungal AgentsDisinfectantsEthanolFluconazoleHydrogen PeroxideSodium Dodecyl Sulfate

Identifiers

PMID18573927
PMCPMC2533490

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.