ArticleJournal of chromatography. B, Analytical technologies in the biomedical and life sciences2008
High-sensitivity analysis of glycosphingolipids by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight imaging mass spectrometry on transfer membranes.
Article in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 60 citations in OpenAlex.
- Distribution of Antisense Oligonucleotides in Rat Eyeballs Using MALDI Imaging Mass Spectrometry.Mass spectrometry (Tokyo, Japan) · 2018Article
- Lipidomics analysis revealed the phospholipid compositional changes in muscle by chronic exercise and high-fat diet.Scientific reports · 2013Article
- Bio-recognition and functional lipidomics by glycosphingolipid transfer technology.Proceedings of the Japan Academy. Series B, Physical and biological sciences · 2013Review
- Scientific literature addressing detection of monosialoganglioside: A 10-year bibliometric analysis.Neural regeneration research · 2012Article
- Preparation and electrophoretic separation of Bodipy-Fl-labeled glycosphingolipids.Journal of chromatography. A · 2012Article
- Sphingolipid and glycosphingolipid metabolic pathways in the era of sphingolipidomics.Chemical reviews · 2011Review
- MALDI imaging of lipid biochemistry in tissues by mass spectrometry.Chemical reviews · 2011Article
- From whole-body sections down to cellular level, multiscale imaging of phospholipids by MALDI mass spectrometry.Molecular & cellular proteomics : MCP · 2011Article
- An introduction to sphingolipid metabolism and analysis by new technologies.Neuromolecular medicine · 2010Review
- Imaging mass spectrometry with silver nanoparticles reveals the distribution of fatty acids in mouse retinal sections.Journal of the American Society for Mass Spectrometry · 2010Article
- Developments and applications of mass microscopy.Medical molecular morphology · 2010Review
- Matrix-assisted laser desorption/ionization imaging mass spectrometry.International journal of molecular sciences · 2010Review
- Medical molecular morphology with imaging mass spectrometry.Medical molecular morphology · 2009Article
- Organ-specific distributions of lysophosphatidylcholine and triacylglycerol in mouse embryo.Lipids · 2009Article
- Imaging mass spectrometry: principle and application.Biophysical reviews · 2009Review
- Multi-dimensional mass spectrometry-based shotgun lipidomics and novel strategies for lipidomic analyses.Mass spectrometry reviewsReview
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
Abstract
Glycosphingolipids are ubiquitous constituents of cells. Yet there is still room for improvement in the techniques for analyzing glycosphingolipids. Here we report our highly sensitive and convenient analytical technology with imaging mass spectrometry for detailed structural analysis of glycosphingolipids. We were able to determine detailed ceramide structures; i.e., both the sphingosine base and fatty acid, by MS/MS/MS analysis on a PVDF membrane with 10 pmol of GM1, with which only faint bands were visible by primuline staining. The limit of detection was approximately 1 pmol of GM1, which is lower than the value in the conventional reports (10 pmol).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.