ArticleJournal of bacteriology2008
Genome-wide analysis of ruminant Staphylococcus aureus reveals diversification of the core genome.
Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
30 citing papers in PubMed, 62 citations in OpenAlex.
- Article
- The spread and antimicrobial resistance of Staphylococcus aureus in South African dairy herds - A review.The Onderstepoort journal of veterinary research · 2021Review
- Multilocus sequence analysis reveals genetic diversity in Staphylococcus aureus isolate of goat with mastitis persistent after treatment with enrofloxacin.Scientific reports · 2021Article
- Review
- Extracellular vesicles produced by human and animal Staphylococcus aureus strains share a highly conserved core proteome.Scientific reports · 2020Article
- The Role of Gram-Positive Surface Proteins in Bacterial Niche- and Host-Specialization.Frontiers in microbiology · 2020Review
- Exfoliative toxin E, a new Staphylococcus aureus virulence factor with host-specific activity.Scientific reports · 2019Article
- Isoenzymatic genotyping of Staphylococcus aureus from dairy cattle and human clinical environments reveal evolutionary divergences.Revista do Instituto de Medicina Tropical de Sao Paulo · 2018Article
- Genomic differences between nasal Staphylococcus aureus from hog slaughterhouse workers and their communities.PloS one · 2018Article
- Characterization of Staphylococcus aureus isolates from raw milk sources in Victoria, Australia.BMC microbiology · 2016Article
- Article
- Fine-tuned characterization of Staphylococcus aureus Newbould 305, a strain associated with mild and chronic mastitis in bovines.Veterinary research · 2014Article
- Staphylococcus aureus from 152 cases of bovine, ovine and caprine mastitis investigated by Multiple-locus variable number of tandem repeat analysis (MLVA).Veterinary research · 2014Article
- Comparative genomics of methicillin-resistant Staphylococcus aureus ST239: distinct geographical variants in Beijing and Hong Kong.BMC genomics · 2014Article
- Global distribution and diversity of ovine-associated Staphylococcus aureus.Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases · 2014Article
- CPRMethicillin resistant coagulase-negative staphylococci isolated from South Korean ducks exhibiting tremor.Acta veterinaria Scandinavica · 2013Article
- Inhibition of Staphylococcus aureus invasion into bovine mammary epithelial cells by contact with live Lactobacillus casei.Applied and environmental microbiology · 2013Article
- Staphylococcus aureus-induced G2/M phase transition delay in host epithelial cells increases bacterial infective efficiency.PloS one · 2013Article
- Genome sequence of Staphylococcus aureus Newbould 305, a strain associated with mild bovine mastitis.Journal of bacteriology · 2012Article
- Antimicrobial susceptibility and molecular subtypes of Staphylococcus aureus isolated from pig tonsils and cow's milk in China.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2012Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
Abstract
Staphylococcus aureus causes disease in humans and a wide array of animals. Of note, S. aureus mastitis of ruminants, including cows, sheep, and goats, results in major economic losses worldwide. Extensive variation in genome content exists among S. aureus pathogenic clones. However, the genomic variation among S. aureus strains infecting different animal species has not been well examined. To investigate variation in the genome content of human and ruminant S. aureus, we carried out whole-genome PCR scanning (WGPS), comparative genomic hybridizations (CGH), and the directed DNA sequence analysis of strains of human, bovine, ovine, and caprine origin. Extensive variation in genome content was discovered, including host- and ruminant-specific genetic loci. Ovine and caprine strains were genetically allied, whereas bovine strains were heterogeneous in gene content. As expected, mobile genetic elements such as pathogenicity islands and bacteriophages contributed to the variation in genome content between strains. However, differences specific for ruminant strains were restricted to regions of the conserved core genome, which contained allelic variation in genes encoding proteins of known and unknown function. Many of these proteins are predicted to be exported and could play a role in host-pathogen interactions. The genomic regions of difference identified by the whole-genome approaches adopted in the current study represent excellent targets for studies of the molecular basis of S. aureus host adaptation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.