ArticleJournal of bacteriology2008
Autoregulation of swrAA and motility in Bacillus subtilis.
Article in Journal of bacteriology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Spx inhibits expression of the SwrA•DegU master flagellar activator inJournal of bacteriology · 2026Article
- SwrA-mediated Multimerization of DegU and an Upstream Activation Sequence Enhance Flagellar Gene Expression in Bacillus subtilis.Journal of molecular biology · 2024Article
- Density and temperature controlled fluid extraction in a bacterial biofilm is determined by poly-γ-glutamic acid production.NPJ biofilms and microbiomes · 2022Article
- Extracellular lipopeptide bacillomycin L regulates serial expression of genes for modulating multicellular behavior in Bacillus velezensis Bs916.Applied microbiology and biotechnology · 2021Article
- Molecular and Cell Biological Analysis of SwrB in Bacillus subtilis.Journal of bacteriology · 2021Article
- Disruption of the pleiotropic gene scoC causes transcriptomic and phenotypical changes in Bacillus pumilus BA06.BMC genomics · 2019Article
- The C-Terminal Region of Bacillus subtilis SwrA Is Required for Activity and Adaptor-Dependent LonA Proteolysis.Journal of bacteriology · 2018Article
- A genetic switch controls the production of flagella and toxins in Clostridium difficile.PLoS genetics · 2017Article
- Role of Hsp100/Clp Protease Complexes in Controlling the Regulation of Motility in Bacillus subtilis.Frontiers in microbiology · 2016Article
- Escape from Lethal Bacterial Competition through Coupled Activation of Antibiotic Resistance and a Mobilized Subpopulation.PLoS genetics · 2015Article
- Shelter in a Swarm.Journal of molecular biology · 2015Review
- Global analysis of mRNA decay intermediates in Bacillus subtilis wild-type and polynucleotide phosphorylase-deletion strains.Molecular microbiology · 2014Article
- The structure and regulation of flagella in Bacillus subtilis.Annual review of genetics · 2014Review
- Article
- A mechanical signal transmitted by the flagellum controls signalling in Bacillus subtilis.Molecular microbiology · 2013Article
- Swarming: flexible roaming plans.Journal of bacteriology · 2013Review
- More than motility: Salmonella flagella contribute to overriding friction and facilitating colony hydration during swarming.Journal of bacteriology · 2013Article
- Article
- A σD-dependent antisense transcript modulates expression of the cyclic-di-AMP hydrolase GdpP in Bacillus subtilis.Microbiology (Reading, England) · 2012Article
- Contribution of surfactin and SwrA to flagellin expression, swimming, and surface motility in Bacillus subtilis.Applied and environmental microbiology · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We demonstrate that transcription of the gene swrAA, required for swarming migration in Bacillus subtilis, is driven by two promoters: a sigD-dependent promoter and a putative sigA-dependent promoter, which is inactive during growth in liquid Luria-Bertani medium and becomes active in the presence of the phosphorylated form of the response regulator DegU or on semisolid surfaces. Since sigD transcription is enhanced by SwrAA, this finding reveals that swrA expression is controlled by a positive feedback loop. We also demonstrate that the positive action of SwrAA in swimming and swarming motility is prevented in strains carrying a deletion of the two-component system degS-degU and that this effect is independent of swrAA transcription. Therefore, both DegU and SwrAA must be present to achieve full motility in B. subtilis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.