ArticleCerebellum (London, England)2008
The principle of recursive genome function.
Article in Cerebellum (London, England), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed.
- Computational identification of ultra-conserved elements in the human genome: a hypothesis on homologous DNA pairing.NAR genomics and bioinformatics · 2024Article
- The Fractal Geometry of the Brain: AnOverview.Advances in neurobiology · 2024Article
- The key role of vasa vasorum inherited remodeling in QBS microcirculatory theory of atherosclerosis.Frontiers in genetics · 2013Article
- Molecular epigenetics, chromatin, and NeuroAIDS/HIV: immunopathological implications.Bioinformation · 2008Article
- Molecular epigenetics, chromatin, and NeuroAIDS/HIV: translational implications.Bioinformation · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Responding to an open request, the principle of recursive genome function (PRGF) is put forward, effectively reversing two axioms of genomics as we used to know it, prior to the Encyclopedia of DNA Elements Project (ENCODE). The PRGF is based on the reversal of the interlocking but demonstrably invalid central dogma and "Junk DNA" conjectures that slowed down the advance of sound theory of genome function, as far as information science is concerned, for half a century. PRGF illustrates the utility of the class of recursive algorithms as the intrinsic mathematics of post-ENCODE genomics. A specific recursive algorithmic approach to PRGF governing the growth of the Purkinje neuron is sketched, building the structure in a hierarchical manner, starting from primary genomic information packets and in each recursion using auxiliary genomic information packets, cancelled upon perusal. The predictive power of the principle and its experimental support are indicated. It is argued that genomics is no longer an exceptional instance of the applicability of recursion throughout the sciences.
Indexed as
Identifiers
18566877What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.