Evidence map›Paper›PMID 18565863›Full record

ReviewThe New England journal of medicine2008

Cancer immunology.

Olivera J Finn

Registry-linked trialAbstract readReview
PubMed Publisher
In one paragraph

Review in The New England journal of medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06225284 (A Randomized Phase II Study of Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients), which is not on this map. Cited by 384 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
384citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06225284 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

A Randomized Phase II Study of Neoadjuvant Chemotherapy With or Without GnRH Agonist for Premenopausal Triple-negative Early Breast Cancer Patients: ESCALATE Study

TypeinterventionalSponsorNational Taiwan University HospitalRan2024 to 2030Enrolled124ConditionsTriple Negative Breast Cancer, Premenopausal Breast CancerArmsGoserelin Acetate 3.6mg、Goserelin Acetate 10.8mg、Leuprolide Acetate 3.75mg、Leuprorelin Acetate 22.5mg、Triptorelin pamoate 11.25mg、Triptorelin pamoate 22.5mg
3 · Its place in the literature

Who cites it

384 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. A Systematic Review and Meta-analysis of Associations between Clinical Prostatitis and Prostate Cancer: New Estimates Accounting for Detection Bias.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2019
    Pooled it
  4. Pooled it
  5. Pooled it
  6. Pooled it
  7. Trial
  8. FCGR Polymorphisms Influence Response to IL2 in Metastatic Renal Cell Carcinoma.Clinical cancer research : an official journal of the American Association for Cancer Research · 2017
    Trial
  9. Article
  10. Targeting Cancer Hallmarks withInternational journal of molecular sciences · 2026
    Review
  11. Cardiotoxicity of T cell immunotherapies.Nature reviews. Cardiology · 2026
    Review
  12. Review
  13. Review
  14. T cell adaptation in chronic infections and tumors.Cellular & molecular immunology · 2026
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Review

324 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Olivera J FinnDepartment of Immunology, University of Pittsburgh School of Medicine, E1044, Biomedical Science Tower, Pittsburgh, PA 15261, USA. ojfinn@pitt.edu

Funding

Vitamin D3 Modulation of Inflammation and Lung Cancer RiskP50CA090440 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DACIC, SANJA · 2001 to 2015
$34.6M
MECHANISMS OF DENDRITIC CELL BASED TUMOR IMMUNIZATIONP01CA073743 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINN, OLIVERA J · 1998 to 2009
$12.3M
T CELL IMMUNITY TO EPITHELIAL TUMOR MUCINSR01CA056103 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINN, OLIVERA J · 1991 to 2013
$3.4M
Dendritic Cell Biology and TherapyR01CA168392 · NCI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FINN, OLIVERA J · 2011 to 2015
$2.0M
NCI NIH HHS P01 CA073743NCI NIH HHS P50 CA090440NCI NIH HHS R01 CA056103NCI NIH HHS R01 CA168392
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cancer VaccinesImmunotherapyAnimalsAntibodies, MonoclonalAntineoplastic AgentsCombined Modality TherapyDisease ProgressionHumansImmune ToleranceNeoplasmsT-LymphocytesAntibodies, MonoclonalAntineoplastic AgentsCancer Vaccines

Identifiers

PMID18565863

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.