ReviewJournal of molecular and cellular cardiology2008
Cardiomyogenic stem and progenitor cell plasticity and the dissection of cardiopoiesis.
Review in Journal of molecular and cellular cardiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed.
- Development of an Injectable Shear-Thinning Nanocomposite Hydrogel for Cardiac Tissue Engineering.Gels (Basel, Switzerland) · 2022Article
- Article
- Opioid receptors and opioid peptides in the cardiomyogenesis of mouse embryonic stem cells.Journal of cellular physiology · 2019Article
- Human stem cells for modeling heart disease and for drug discovery.Science translational medicine · 2014Review
- Small molecule cardiogenol C upregulates cardiac markers and induces cardiac functional properties in lineage-committed progenitor cells.Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology · 2014Article
- Establishment and characterization of the reversibly immortalized mouse fetal heart progenitors.International journal of medical sciences · 2013Article
- Ca2+ activated K channels-new tools to induce cardiac commitment from pluripotent stem cells in mice and men.Stem cell reviews and reports · 2012Article
- Linkage of cardiac gene expression profiles and ETS2 with lifespan variability in rats.Aging cell · 2012Article
- Production of de novo cardiomyocytes: human pluripotent stem cell differentiation and direct reprogramming.Cell stem cell · 2012Article
- Molecular mechanisms of cardiomyocyte aging.Clinical science (London, England : 1979) · 2011Review
- Differentiation induction of mouse embryonic stem cells into sinus node-like cells by suramin.International journal of cardiology · 2011Article
- Present state and future perspectives of using pluripotent stem cells in toxicology research.Archives of toxicology · 2011Review
- An inducible expression system of the calcium-activated potassium channel 4 to study the differential impact on embryonic stem cells.Stem cells international · 2011Article
- Embryonic stem cell-derived cardiomyocyte heterogeneity and the isolation of immature and committed cells for cardiac remodeling and regeneration.Stem cells international · 2011Article
- Telocytes in human epicardium.Journal of cellular and molecular medicine · 2010Article
- Pluripotency of human embryonic and induced pluripotent stem cells for cardiac and vascular regeneration.Thrombosis and haemostasis · 2010Review
- Cardiac renewing: interstitial Cajal-like cells nurse cardiomyocyte progenitors in epicardial stem cell niches.Journal of cellular and molecular medicine · 2009Article
- Enhanced proliferation of monolayer cultures of embryonic stem (ES) cell-derived cardiomyocytes following acute loss of retinoblastoma.PloS one · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Cell-based therapies hold promise of repairing an injured heart, and the description of stem and progenitor cells with cardiomyogenic potential is critical to its realization. At the vanguard of these efforts are analyses of embryonic stem cells, which clearly have the capacity to generate large numbers of cardiomyocytes in vitro. Through the use of this model system, a number of signaling mechanisms have been worked out that describes at least partially the process of cardiopoiesis. Studies on adult stem and on progenitor cells with cardiomyogenic potential are still in their infancy, and much less is known about the molecular signals that are required to induce the differentiation to cardiomyocytes. It is also unclear whether the pathways are similar or different between embryonic and adult cell-induced cardiomyogenesis, partly because of the continued controversies that surround the stem cell theory of cardiac self-renewal. Irrespective of any perceived or actual limitations, the study of stem and progenitor cells has provided important insights into the process of cardiomyogenesis, and it is likely that future research in this area will turn the promise of repairing an injured heart into a reality.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.