ArticleJournal of perinatology : official journal of the California Perinatal Association2008
Association of BPD and IVH with early neutrophil and white counts in VLBW neonates with gestational age <32 weeks.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00005289 (Risk Factors in Bronchopulmonary Dysplasia), which is not on this map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Risk Factors in Bronchopulmonary Dysplasia (Newborn Lung Project)
Who cites it
6 citing papers in PubMed, 17 citations in OpenAlex.
- Investigation of the miRNA-mRNA Regulatory Circuits and Immune Signatures Associated with Bronchopulmonary Dysplasia.Journal of inflammation research · 2024Article
- Association of immune cell recruitment and BPD development.Molecular and cellular pediatrics · 2022Review
- Blunted cardiac output response to exercise in adolescents born preterm.European journal of applied physiology · 2020Article
- Neonatal hematological parameters and the risk of moderate-severe bronchopulmonary dysplasia in extremely premature infants.BMC pediatrics · 2019Article
- Impaired autonomic function in adolescents born preterm.Physiological reports · 2018Article
- Late-onset neutropenia: defining limits of neutrophil count in very low birth weight infants.Journal of perinatology : official journal of the California Perinatal Association · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate associations between early low neutrophil count from routine blood samples, white blood count (WBC), pregnancy complications and neonatal outcomes for very low birth weight infants (VLBW <or=1500 g) with gestational age <32 weeks. STUDY
designInformation was abstracted on all infants admitted to level III neonatal intensive care units in Wisconsin 2003 to 2004. A total of 1002 VLBW neonates (78%) had differential and corrected total white counts within 2 (1/2) h of birth. Data analyses included frequency tables, binary logistic, ordinal logistic and ordinary regression.
resultLow neutrophil count (<1000 per microl) was strongly associated with low WBC, pregnancy complications and antenatal steroids. Low neutrophil count predicted bronchopulmonary dysplasia severity level (odds ratio, OR: 1.7, 95% confidence interval, CI: 1.1 to 2.7) and intraventricular hemorrhage grade (OR: 2.2, 95% CI: 1.3 to 3.8).
conclusionEarly neutrophil counts may have multiple causes interfering with their routine use as an inflammatory marker. Nonetheless, low neutrophil count has consistent independent associations with outcomes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.