ArticleGenetics2008
Comparative analyses of human single- and multilocus tandem repeats.
Article in Genetics, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
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Who cites it
14 citing papers in PubMed, 26 citations in OpenAlex.
- Genetic Redundancy in Rye Shows in a Variety of Ways.Plants (Basel, Switzerland) · 2023Review
- The Cytogenetic Map of the Nile Crocodile (International journal of molecular sciences · 2022Article
- Mouse chromocenters DNA content: sequencing and in silico analysis.BMC genomics · 2018Article
- Repetitive DNA loci and their modulation by the non-canonical nucleic acid structures R-loops and G-quadruplexes.Nucleus (Austin, Tex.) · 2017Review
- Polycomb repressive complex 1 provides a molecular explanation for repeat copy number dependency in FSHD muscular dystrophy.Human molecular genetics · 2017Article
- The expansion of heterochromatin blocks in rye reflects the co-amplification of tandem repeats and adjacent transposable elements.BMC genomics · 2016Article
- Tandem amplification of a chromosomal segment harboring 5-enolpyruvylshikimate-3-phosphate synthase locus confers glyphosate resistance in Kochia scoparia.Plant physiology · 2014Article
- Direct mapping of symbolic DNA sequence into frequency domain in global repeat map algorithm.Nucleic acids research · 2013Article
- Coevolution between simple sequence repeats (SSRs) and virus genome size.BMC genomics · 2012Article
- A repetitive elements perspective in Polycomb epigenetics.Frontiers in genetics · 2012Article
- Transposable elements are a significant contributor to tandem repeats in the human genome.Comparative and functional genomics · 2012Article
- Tandemly repeated DNA families in the mouse genome.BMC genomics · 2011Article
- TRStalker: an efficient heuristic for finding fuzzy tandem repeats.Bioinformatics (Oxford, England) · 2010Article
- Analysis of the largest tandemly repeated DNA families in the human genome.BMC genomics · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
Using the compiled human genome sequence, we systematically cataloged all tandem repeats with periods between 20 and 2000 bp and defined two subsets whose consensus sequences were found at either single-locus tandem repeats (slTRs) or multilocus tandem repeats (mlTRs). Parameters compiled for these subsets provide insights into mechanisms underlying the creation and evolution of tandem repeats. Both subsets of tandem repeats are nonrandomly distributed in the genome, being found at higher frequency at many but not all chromosome ends and internal clusters of mlTRs were also observed. Despite the integral role of recombination in the biology of tandem repeats, recombination hotspots colocalized only with shorter microsatellites and not the longer repeats examined here. An increased frequency of slTRs was observed near imprinted genes, consistent with a functional role, while both slTRs and mlTRs were found more frequently near genes implicated in triplet expansion diseases, suggesting a general instability of these regions. Using our collated parameters, we identified 2230 slTRs as candidates for highly informative molecular markers.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.