Evidence map›Paper›PMID 18562582›Full record

ArticleJournal of clinical microbiology2008

Geographic distribution and antifungal susceptibility of the newly described species Candida orthopsilosis and Candida metapsilosis in comparison to the closely related species Candida parapsilosis.

Shawn R Lockhart, Shawn A Messer, Michael A Pfaller, Daniel J Diekema

Abstract readComparative Study
In one paragraph

Article in Journal of clinical microbiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 86 papers.

0numbers the graph read from it
0cells of the map it votes in
86citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

86 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Microorganisms · 2025
    Review
  5. Article
  6. Article
  7. Threats from theMicrobiology and molecular biology reviews : MMBR · 2024
    Review
  8. Review
  9. Article
  10. Article
  11. Saprochaete/Magnusiomyces: identification, virulence factors, and antifungal susceptibility of a challenging rare yeast.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2024
    Article
  12. The Emerging PathogenInfection and drug resistance · 2024
    Review
  13. Article
  14. Review
  15. Molecular Investigation of the Fatal BloodstreamInternational journal of molecular sciences · 2023
    Article
  16. FatalJournal of fungi (Basel, Switzerland) · 2022
    Article
  17. Global Prevalence of Antifungal-ResistantTropical medicine and infectious disease · 2022
    Review
  18. Article
  19. Genetic Manipulation as a Tool to UnravelJournal of fungi (Basel, Switzerland) · 2021
    Review
  20. Article

26 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shawn R LockhartDepartment of Pathology, University of Iowa Carver College of Medicine, University of Iowa Hospitals and Clinics, 6008 BT GH, 200 Hawkins Drive, Iowa City, IA 52242-1009, USA. shawn-lockhart@uiowa.edu
Shawn A Messer
Michael A Pfaller
Daniel J Diekema

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Candida orthopsilosis and Candida metapsilosis are recently described species, having previously been grouped with the more prevalent species Candida parapsilosis. Current literature contains very little data pertaining to the distributions and antifungal susceptibilities of these Candida species. We determined the species and antifungal susceptibilities of 1,929 invasive clinical isolates from the ARTEMIS antifungal surveillance program collected between 2001 and 2006 and identified as C. parapsilosis using Vitek and conventional methods. Of the 1,929 isolates of presumed C. parapsilosis tested, 117 (6.1%) were identified as C. orthopsilosis and 34 (1.8%) as C. metapsilosis. The percentage of presumed C. parapsilosis isolates found to be C. orthopsilosis varied greatly by region, with the highest percentage (10.9%) from South America and the lowest (0.7%) from Africa. The MIC distributions of the C. orthopsilosis and C. metapsilosis isolates were statistically significantly lower than those of C. parapsilosis for all drugs except fluconazole, for which they were significantly higher (P < 0.001 for all). No C. orthopsilosis or C. metapsilosis isolates were fluconazole resistant, and all were susceptible to caspofungin, anidulafungin, and micafungin.

Indexed as

AdolescentAdultAfricaAgedAged, 80 and overAntifungal AgentsCandidaCandidiasisChildChild, PreschoolDrug Resistance, FungalGeographyHumansInfantInfant, NewbornMicrobial Sensitivity TestsAntifungal Agents

Identifiers

PMID18562582
PMCPMC2519489

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.