ArticleProceedings of the National Academy of Sciences of the United States of America2008
4D visualization of embryonic, structural crystallization by single-pulse microscopy.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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4 citing papers in PubMed, 44 citations in OpenAlex.
- Observing in space and time the ephemeral nucleation of liquid-to-crystal phase transitions.Nature communications · 2015Article
- Macromolecular structural dynamics visualized by pulsed dose control in 4D electron microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2011Article
- Scanning ultrafast electron microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
- Biological imaging with 4D ultrafast electron microscopy.Proceedings of the National Academy of Sciences of the United States of America · 2010Article
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5 authors at 1 institution in 1 country.
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Abstract
In many physical and biological systems the transition from an amorphous to ordered native structure involves complex energy landscapes, and understanding such transformations requires not only their thermodynamics but also the structural dynamics during the process. Here, we extend our 4D visualization method with electron imaging to include the study of irreversible processes with a single pulse in the same ultrafast electron microscope (UEM) as used before in the single-electron mode for the study of reversible processes. With this augmentation, we report on the transformation of amorphous to crystalline structure with silicon as an example. A single heating pulse was used to initiate crystallization from the amorphous phase while a single packet of electrons imaged selectively in space the transformation as the structure continuously changes with time. From the evolution of crystallinity in real time and the changes in morphology, for nanosecond and femtosecond pulse heating, we describe two types of processes, one that occurs at early time and involves a nondiffusive motion and another that takes place on a longer time scale. Similar mechanisms of two distinct time scales may perhaps be important in biomolecular folding.
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