ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2008
Impact of comorbid diabetes on quality of life and perception of angina pain in people with angina registered with general practitioners in the UK.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 7 citations in OpenAlex.
- Health-related quality of life and preferred health-seeking institutions among rural elderly individuals with and without chronic conditions: a population-based study in Guangdong Province, China.BioMed research international · 2014Article
- Health-related quality of life and long-term care needs among elderly individuals living alone: a cross-sectional study in rural areas of Shaanxi Province, China.BMC public health · 2013Article
- Combined impact of geriatric syndromes and cardiometabolic diseases on measures of functional impairment.The journals of gerontology. Series A, Biological sciences and medical sciences · 2011Article
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsTo investigate the impact of comorbid diabetes on general and angina-related quality of life (QoL) in people with angina.
methodsWe analysed data for a subset of patients with angina, from a randomised controlled trial conducted in UK primary care. SF36 scores and Seattle Angina Questionnaire scores were compared for people with and without diabetes. We adopted a robust statistical approach, using nonparametric quantile regression to adjust for the influence of potential confounders.
resultsData were available for 904 cases of whom 181 (20%) had diabetes. Presence of comorbid diabetes was significantly associated with reduced generic QoL for all SF36 domains and Seattle Angina Questionnaire physical limitation scores (estimated regression coefficient -12.33), but not for the other angina-related scores. Greater frequency of perceived angina was strongly correlated with reduced QoL (P<0.001) and angina frequency was similar in people with and without diabetes (P=0.576).
conclusionsOur results confirm the cumulative impact of having multiple chronic diseases on QoL. Though limited by the data available, our finding of similar angina frequency in patients with and without diabetes contributes to the debate regarding the influence of autonomic neuropathy on perception of angina in people with diabetes.
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