Evidence map›Paper›PMID 18560844›Full record

ArticleInternational journal of colorectal disease2008

Radiological evaluation of colorectal anastomoses.

A Doeksen, P J Tanis, A F J Wüst, B C Vrouenraets, J J B van Lanschot, W F van Tets

Registry-linked trialAbstract readComparative Study
In one paragraph

Article in International journal of colorectal disease, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03013153 (Low or High Ligation of the Inferior Mesenteric Artery With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03013153 naunknown statusnot on this mapstarted 2016, after this paper: background citation

Low or High Ligation of the Inferior Mesenteric Artery With Apical Lymph Node Dissection in Rectal Cancer Laparoscopic Surgery: A Prospective, Multi-Center, Randomized, Open-Label, Parallel Group, Non-Inferiority Clinical Trial (LAND)

TypeinterventionalSponsorSixth Affiliated Hospital, Sun Yat-sen UniversityRan2016 to 2023Enrolled748ConditionsRectal CancerArmsLow ligation with apical lymph node dissection, High ligation
3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Frontiers in surgery · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. The importance of rectal contrast in CT assessment to detect anastomotic leakage after colorectal surgery.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2021
    Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. [Diagnosis and definition of anastomotic leakage from the radiologist's perspective].Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen · 2011
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

A DoeksenDepartment of Surgery, Sint Lucas Andreas Hospital, Jan Tooropstraat 164, 1006 AE, Amsterdam, the Netherlands.
P J Tanis
A F J Wüst
B C Vrouenraets
J J B van Lanschot
W F van Tets

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe purpose of this study was to determine the accuracy, interobserver variability, timing and discordance with relaparotomy of postoperative radiological examination of colorectal anastomoses. PATIENT/

methodsFrom 2000 to 2005, 429 patients underwent an ileocolonic, colo-colonic, or colorectal anastomosis. Radiological examination of the anastomosis was not performed routinely, but only when there were clinically signs of leakage. Radiological imaging was reviewed by an independent radiologist and medical records were retrospectively analyzed. Clinical anastomotic leakage was the standard of reference and defined as leakage confirmed during relaparotomy, drainage of pus per anum or as an anastomotic defect identified at digital examination.

resultsRadiological evaluation of the anastomosis was performed in 91 patients (21%): CT in 27 patients, contrast radiography in 40, and both imaging modalities in 24 patients. The interobserver variability of CT and contrast radiography was 10% and 14%, respectively. The sensitivity and negative predictive value of imaging of the anastomosis was 65% and 73%, respectively. Anastomotic leakage was found in 11 of 21 patients (52%) who underwent relaparotomy despite negative imaging. Three of 36 patients (8%) with a diagnosis of anastomotic leakage based on radiological examination had an intact anastomosis at relaparotomy.

conclusionRadiological imaging of the anastomosis after colorectal surgery should be restrictively applied and interpreted with caution because of the high false-negative rate and the substantial interobserver variability.

Indexed as

Anastomosis, SurgicalColonColonic DiseasesFollow-Up StudiesHumansObserver VariationRadiography, AbdominalRectal DiseasesRectumReproducibility of ResultsRetrospective StudiesTomography, X-Ray Computed

Identifiers

PMID18560844
PMCPMC2493516

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.