Evidence map›Paper›PMID 18559645›Full record

ArticleAntimicrobial agents and chemotherapy2008

Evaluation of Etest method for determining isavuconazole MICs against Cryptococcus gattii and Cryptococcus neoformans.

George R Thompson, Annette W Fothergill, Nathan P Wiederhold, Ana C Vallor, Brian L Wickes, Thomas F Patterson

Abstract readEvaluation Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Methods for Antifungal Susceptibility Testing of theJournal of fungi (Basel, Switzerland) · 2023
    Review
  2. New Perspectives on Antimicrobial Agents: Isavuconazole.Antimicrobial agents and chemotherapy · 2022
    Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Cryptococcus gattii infections.Clinical microbiology reviews · 2014
    Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

George R ThompsonDepartment of Internal Medicine, Division of Infectious Diseases, UTHSCSA, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA. thompsong2@uthscsa.edu
Annette W Fothergill
Nathan P Wiederhold
Ana C Vallor
Brian L Wickes
Thomas F Patterson

Funding

PHS HHS N0I-A1-25475
6 · The paper itself

Abstract

We compared Etest with broth microdilution testing for isavuconazole activity against 92 Cryptococcus isolates. A 97.8% agreement was found between these methods, without major discrepancies (>2-well dilution difference). Our findings support the use of the Etest methodology as a reliable method for the determination of MICs against Cryptococcus spp.

Indexed as

Antifungal AgentsCryptococcusCryptococcus neoformansMicrobial Sensitivity TestsNitrilesPyridinesReproducibility of ResultsSpecies SpecificityTriazolesAntifungal AgentsisavuconazoleNitrilesPyridinesTriazoles

Identifiers

PMID18559645
PMCPMC2493144

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.