Evidence map›Paper›PMID 18559115›Full record

ArticleBMC health services research2008

Antihypertensive medication prescription patterns and time trends for newly-diagnosed uncomplicated hypertension patients in Taiwan.

Pang-Hsiang Liu, Jung-Der Wang

Abstract read
In one paragraph

Article in BMC health services research, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

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0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Non-persistence to antihypertensive drug therapy in Lithuania.European journal of clinical pharmacology · 2022
    Article
  4. Review
  5. Article
  6. Article
  7. The Use of Dried Blood Spots for the Quantification of Antihypertensive Drugs.International journal of analytical chemistry · 2018
    Review
  8. Observational
  9. Article
  10. Article
  11. Article
  12. Systolic hypertension: an increasing clinical challenge in Asia.Hypertension research : official journal of the Japanese Society of Hypertension · 2015
    Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

2 authors.

Pang-Hsiang LiuInstitute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan. d94841004@ntu.edu.tw
Jung-Der Wang

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKnowledge of existing prescription patterns in the treatment of newly-diagnosed hypertension can provide useful information for improving clinical practice in this field. The aims of this study are to determine the prescription patterns and time trends for antihypertensive medication in newly-diagnosed cases of uncomplicated hypertension in Taiwan and to compare these with current clinical guidelines.

methodsA total of 6,536 newly-diagnosed patients with uncomplicated hypertension, aged >/=30 years, were identified from the representative 200,000-person sample in the computerized reimbursement database of the National Health Insurance in Taiwan. These patients were followed from 1998 to 2004 with all diagnoses, prescription data and medication charges being retrieved for subsequent analysis.

resultsPrescription patterns varied by age, gender and clinical facilities, with mono-therapies being found to be dominant in the first year, albeit declining over time. Calcium channel blockers and beta-blockers were the most frequently prescribed antihypertensive drugs, either alone or in combinations. Although least expensive, the prescription rates of diuretics were low, at 8.3% for mono-therapies and 19.9% overall. The prescription rate for angiotensin receptor blockers (ARBs) was elevated considerably over time. After controlling for other related factors by multiple logistic regression analysis, ARBs were found to be prescribed mainly by medical centers or regional hospitals.

conclusionThese findings indicate the existence of a gap between current clinical practice and the desired goal of cost-effectiveness in antihypertensive treatment in Taiwan, which should be corrected.

Indexed as

Antihypertensive AgentsComorbidityDrug CostsDrug PrescriptionsDrug Therapy, CombinationFemaleHumansHypertensionMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Sex FactorsTaiwanAntihypertensive Agents

Identifiers

PMID18559115
PMCPMC2443138

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.