ArticleBMJ (Clinical research ed.)2008
Case-control study of self reported genitourinary infections and risk of gastroschisis: findings from the national birth defects prevention study, 1997-2003.
Article in BMJ (Clinical research ed.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 90 citations in OpenAlex.
- County-Level Atrazine Use and Gastroschisis.JAMA network open · 2024Article
- Maternal diabetes mellitus and birth defects in Taiwan: A 5-year nationwide population-based cohort study.Journal of the Chinese Medical Association : JCMA · 2023Article
- Reducing Birth Defects by Decreasing the Prevalence of Maternal Chronic Diseases-Evaluated by Linked National Registration Dataset.Children (Basel, Switzerland) · 2022Article
- Maternal occupational exposure to solvents and gastroschisis in offspring - National Birth Defects Prevention Study 1997-2011.Occupational and environmental medicine · 2020Article
- Risk of gastroschisis with maternal genitourinary infections: the US National birth defects prevention study 1997-2011.BMJ open · 2019Article
- Maternal genitourinary infections and risk of birth defects in the National Birth Defects Prevention Study.Birth defects research · 2018Article
- Gastroschisis and Cumulative Stressor Exposures.Epidemiology (Cambridge, Mass.) · 2018Article
- Cigarette smoking is associated with an altered vaginal tract metabolomic profile.Scientific reports · 2018Article
- Maternal Antibodies to Chlamydia trachomatis and Risk of Gastroschisis.Birth defects research · 2017Article
- Maternal Antibodies to Herpes Virus Antigens and Risk of Gastroschisis in Offspring.American journal of epidemiology · 2016Article
- Association between antibiotic use among pregnant women with urinary tract infections in the first trimester and birth defects, National Birth Defects Prevention Study 1997 to 2011.Birth defects research. Part A, Clinical and molecular teratology · 2016Article
- The epidemiology, prevalence and hospital outcomes of infants with gastroschisis.Journal of perinatology : official journal of the California Perinatal Association · 2016Article
- Spatial variability of gastroschisis in Canada, 2006-2011: An exploratory analysis.Canadian journal of public health = Revue canadienne de sante publique · 2016Article
- Trimethoprim-sulfonamide use during the first trimester of pregnancy and the risk of congenital anomalies.Pharmacoepidemiology and drug safety · 2016Article
- Chlamydia trachomatis IgG3 seropositivity is associated with gastroschisis.Journal of perinatology : official journal of the California Perinatal Association · 2015Article
- Spatial analysis of gastroschisis in the National Birth Defects Prevention Study.Birth defects research. Part A, Clinical and molecular teratology · 2015Article
- Spatial analysis of gastroschisis in Massachusetts and Texas.Annals of epidemiology · 2015Article
- Maternal genitourinary infections and the risk of gastroschisis.American journal of epidemiology · 2014Article
- Violence against women and gastroschisis: a case-control study.International journal of environmental research and public health · 2013Article
- The role of maternal stress in early pregnancy in the aetiology of gastroschisis: an incident case control study.PloS one · 2013Article
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveTo assess the association between genitourinary infections in the month before conception to the end of the first trimesterand gastroschisis.
designCase-control study with self reported infections from a computer assisted telephone interview.
settingNational birth defects prevention study, a multisite, population based study including 10 surveillance systems for birth defects in the United States.
participantsMothers of 505 offspring with gastroschisis and 4924 healthy liveborn infants as controls.
main outcome measureAdjusted odds ratios for gastroschisis with 95% confidence intervals.
resultsAbout 16% (n=81) of case mothers and 9% (n=425) of control mothers reported a genitourinary infection in the relevant time period; 4% (n=21) and 2% (n=98) reported a sexually transmitted infection and 13% (n=67) and 7% (n=338) reported a urinary tract infection, respectively. Case mothers aged <25 years reported higher rates of urinary tract infection alone and in combination with a sexually transmitted infection compared with control mothers. In women who reported both types of infection, there was a greater risk of gastroschisis in offspring (adjusted odds ratio 4.0, 95% confidence interval 1.4 to 11.6).
conclusionThere is a significant association between self reported urinary tract infection plus sexually transmitted infection just before conception and in early pregnancy and gastroschisis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.