Evidence map›Paper›PMID 18556606›Full record

SynthesisAmerican journal of public health2008

Effect of hand hygiene on infectious disease risk in the community setting: a meta-analysis.

Allison E Aiello, Rebecca M Coulborn, Vanessa Perez, Elaine L Larson

3 registry-linked trialsOpen access · greenAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in American journal of public health, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 297 papers, 15 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
297citing papers in PubMed, 15 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03454009 nacompletednot on this mapstarted 2018, after this paper: background citation

Kent State University / Price Chopper Wellness Promotion Study

TypeinterventionalSponsorKent State UniversityRan2018 to 2018Enrolled195ConditionsAcute Respiratory Infection, Influenza-like Illness, Gastrointestinal InfectionArmsMultimodal hygiene intervention
NCT03810430 nacompletednot on this mapstarted 2015, after this paper: background citation

Impact of Health Promotion Interventions in Changing Mother's Behavior and Improving Child Health in Hufash District- Al-Mahweet, Yemen

TypeinterventionalSponsorSana'a UniversityRan2015 to 2018Enrolled360ConditionsDiarrhea, NutritionalArmshealth promotion
NCT03942523 naunknown statusnot on this mapstarted 2018, after this paper: background citation

School-based Interventions to Promote Personal and Environmental Hygiene Among Children in Pakistan: Protocol for a Mixed Methods Study

TypeinterventionalSponsorAga Khan UniversityRan2018 to 2020Enrolled256ConditionsBehavioral Assessment of Children, Communicable Diseases in ChildrenArmsBehavior Change Communication to promote hygiene behavior
3 · Its place in the literature

Who cites it

297 citing papers in PubMed, 15 syntheses or guidelines pooled it, 811 citations in OpenAlex.

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  8. A Systematic Review for Effective Preventive Public Education of Respiratory Infection.International journal of environmental research and public health · 2021
    Pooled it
  9. Hand-washing promotion for preventing diarrhoea.The Cochrane database of systematic reviews · 2021
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237 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Allison E AielloDepartment of Epidemiology, Center for Social Epidemiology & Population Health, University of Michigan-School of Public Health, 3659 SPH Tower, 109 Observatory, Ann Arbor, MI 48109-2029, USA. aielloa@umich.edu
Rebecca M Coulborn
Vanessa Perez
Elaine L Larson
University of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To quantify the effect of hand-hygiene interventions on rates of gastrointestinal and respiratory illnesses and to identify interventions that provide the greatest efficacy, we searched 4 electronic databases for hand-hygiene trials published from January 1960 through May 2007 and conducted meta-analyses to generate pooled rate ratios across interventions (N=30 studies). Improvements in hand hygiene resulted in reductions in gastrointestinal illness of 31% (95% confidence intervals [CI]=19%, 42%) and reductions in respiratory illness of 21% (95% CI=5%, 34%). The most beneficial intervention was hand-hygiene education with use of nonantibacterial soap. Use of antibacterial soap showed little added benefit compared with use of nonantibacterial soap. Hand hygiene is clearly effective against gastrointestinal and, to a lesser extent, respiratory infections. Studies examining hygiene practices during respiratory illness and interventions targeting aerosol transmission are needed.

Indexed as

Communicable Disease ControlCommunicable DiseasesCommunity-Acquired InfectionsDatabases, BibliographicGastrointestinal DiseasesHand DisinfectionHumansRespiratory Tract InfectionsRisk AssessmentSkin CareSurface-Active AgentsSurface-Active Agents

Identifiers

PMID18556606
PMCPMC2446461
OpenAlexW2109881331

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.