ReviewMethods (San Diego, Calif.)2008
Brain maps on the go: functional imaging during motor challenge in animals.
Review in Methods (San Diego, Calif.), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 23 citations in OpenAlex.
- Cerebellar Metabolic Connectivity during Treadmill Walking before and after Unilateral Dopamine Depletion in Rats.International journal of molecular sciences · 2024Article
- Cerebral perfusion mapping during retrieval of spatial memory in rats.Behavioural brain research · 2019Article
- Increases in BrainFrontiers in physiology · 2017Article
- Network Patterns Associated with Navigation Behaviors Are Altered in Aged Nonhuman Primates.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2016Article
- Complete protection from impending stroke following permanent middle cerebral artery occlusion in awake, behaving rats.The European journal of neuroscience · 2014Article
- Neonatal +-methamphetamine exposure in rats alters adult locomotor responses to dopamine D1 and D2 agonists and to a glutamate NMDA receptor antagonist, but not to serotonin agonists.The international journal of neuropsychopharmacology · 2013Article
- Functional reorganization of motor and limbic circuits after exercise training in a rat model of bilateral parkinsonism.PloS one · 2013Article
- CNS animal fMRI in pain and analgesia.Neuroscience and biobehavioral reviews · 2011Article
- Mapping functional brain activation using [14C]-iodoantipyrine in male serotonin transporter knockout mice.PloS one · 2011Article
- Powering an implantable minipump with a multi-layered printed circuit coil for drug infusion applications in rodents.Annals of biomedical engineering · 2010Article
- A low power, on demand electrothermal valve for wireless drug delivery applications.Lab on a chip · 2010Article
- A Parylene MEMS Electrothermal Valve.Journal of microelectromechanical systems : a joint IEEE and ASME publication on microstructures, microactuators, microsensors, and microsystems · 2009Article
- Sex differences in functional brain activation during noxious visceral stimulation in rats.Pain · 2009Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Brain mapping in the freely moving animal is useful for studying motor circuits, not only because it avoids the potential confound of sedation or restraints, but because activated brain states may serve to accentuate differences that only manifest partially while a subject is in the resting state. Perfusion or metabolic mapping using autoradiography allows one to examine changes in brain function at the circuit level across the entire brain with a spatial resolution (approximately 100 micro) appropriate for the rat or mouse brain, and a temporal resolution (seconds-minutes) sufficient for capturing acute brain changes. Here we summarize the application of these methods to the functional brain mapping of behaviors involving locomotion of small animals, methods for the three-dimensional reconstruction of the brain from autoradiographic sections, voxel based analysis of the whole brain, and generation of maps of the flattened rat cortex. Application of these methods in animal models promises utility in improving our understanding of motor function in the normal brain, and of the effects of neuropathology and treatment interventions such as exercise have on the reorganization of motor circuits.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.