ArticleClinical rheumatology2008
Decreased bone mineral density in adult familial Mediterranean fever patients: a pilot study.
Article in Clinical rheumatology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Cardiovascular Risk and Bone Mineral Density in Children with Familial Mediterranean Fever: The Role of Disease Severity and Genetic Mutations.International journal of molecular sciences · 2026Article
- Dental Age Estimation by Demirjian, Willems, and Cameriere Methods in Children with Familial Mediterranean Fever: A Case-Control Study.Children (Basel, Switzerland) · 2025Article
- Article
- Osteoporosis in Systemic Autoinflammatory Diseases: A Case-Control Study.Frontiers in endocrinology · 2019Article
- Vitamin D levels in children with familial Mediterranean fever.Pediatric rheumatology online journal · 2016Article
- Bone Mineral Density in Egyptian Children with Familial Mediterranean Fever.Iranian journal of medical sciences · 2016Article
- Serum bone markers levels and bone mineral density in familial mediterranean Fever.Journal of physical therapy science · 2014Article
- Low plasma vitamin D levels in patients with familial Mediterranean fever.Rheumatology international · 2012Article
- Bone mineral density in familial Mediterranean fever.Rheumatology international · 2012Article
- Cephalometric evaluation of children with familial Mediterranean fever.The Angle orthodontist · 2012Article
- Chronic inflammation in FMF: markers, risk factors, outcomes and therapy.Nature reviews. Rheumatology · 2011Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the association between familial Mediterranean fever (FMF) and osteoporosis (OP) in adult patients. Thirty-five attack-free FMF patients (28 females, 7 males; mean age 36.9 +/- 5.7 years) were individually matched to control subjects on the basis of age (within 2 years) and sex. All patients were taking regular colchicine. Subjects having any condition that can cause decreased bone mineral density (BMD) were excluded from the study. BMD was measured at the spine and femur by dual X-ray absorptiometry (DXA). Data was given as the median (IQR). T scores of the spine were -0.700 (-1.097 to -0.262) and -0.450 (-0.830 to 0.112) in FMF patients and healthy controls, respectively (p > 0.05). T scores of the femur neck were -0.900 (-1.480 to -0.570) and -0.430 (-1.472 to 0.247) in FMF patients and healthy controls, respectively (p > 0.05). Total femur T scores were significantly lower in FMF patients than healthy controls (-0.780 [-1.222 to -0.085] vs. -0.100 [-0.765 to 0.537], respectively, p = 0.021). Total femur T scores were significantly decreased in adult patients with FMF. Ongoing subclinical inflammation may be associated with decreased bone mineral content in those patients.
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