Trial reportSao Paulo medical journal = Revista paulista de medicina2008
Tepid sponging plus dipyrone versus dipyrone alone for reducing body temperature in febrile children.
Trial report in Sao Paulo medical journal = Revista paulista de medicina, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.
- Effectiveness and safety of Tuina massage therapy for paediatric fever: a systematic review and meta-analysis of randomised controlled trials.BMC pediatrics · 2025Pooled it
- Definition and assessment of fever-related discomfort in pediatric literature: a systematic review.European journal of pediatrics · 2024Pooled it
- Effectiveness of warm compresses in reducing the temperature of febrile children: A pilot randomized clinical trial.Revista da Escola de Enfermagem da U S P · 2022Trial
- Optimal diagnostic fever thresholds using non-contact infrared thermometers under COVID-19.Frontiers in public health · 2022Article
- Is tepid sponging more effective than paracetamol at relieving fever in febrile children in hot tropical climates? a mini review.Ghana medical journal · 2021Article
- [Correlations between Obtaining Fever Management Information from the Internet and Knowledge and Practices of Fever Management by Mothers of Infants and Toddlers].Child health nursing research · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
CONTEXT AND
objectiveThe role of tepid sponging to promote fever control in children is controversial. We did not find any studies reporting on the effectiveness of tepid sponging in addition to dipyrone. The aim of this study was to compare the effects of tepid sponging plus dipyrone with dipyrone alone for reducing fever. DESIGN AND
settingA randomized clinical trial was undertaken at Instituto Materno-Infantil Professor Fernando Figueira, Recife, Pernambuco.
methodsChildren from six months to five years old with axillary temperature greater than 38 masculineC in the emergency ward between January and July 2006 were eligible. One hundred and twenty children were randomly assigned to receive oral dipyrone (20 mg/kg) or oral dipyrone and tepid sponging for 15 minutes. The primary outcome was mean temperature reduction after 15, 30, 60, 90 and 120 minutes. Secondary outcomes were crying and irritability.
results106 children finished the study. After the first 15 minutes, the fall in axillary temperature was significantly greater in the sponged group than in the control group (p < 0.001). From 30 to 120 minutes, better fever control was observed in the control group. Crying and irritability were observed respectively in 52% and 36% of the sponged children and in none and only two of the controls.
conclusionsTepid sponging plus dipyrone cooled faster during the first 15 minutes, but dipyrone alone presented better fever control over the two-hour period. Tepid sponging caused mild discomfort, crying and irritability for most of the children. CLINICAL TRIAL REGISTRATION NUMBER: ACTRN12608000083392.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.