ArticleJournal of genetic counseling2008
Genetic counseling in southern Iran: consanguinity and reason for referral.
Article in Journal of genetic counseling, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed.
- Experience in prenatal genetic testing and reproductive decision-making for monogenic disorders from a single tertiary care genetics clinic in a low-middle income country.BMC pregnancy and childbirth · 2023Article
- Interventions addressing genetic disease burdens within selected countries in the MENA region: a scoping review.Journal of community genetics · 2023Article
- Next-Generation Sequencing Identifies Pathogenic Variants inNeural plasticity · 2021Article
- Papillon-Lefèvre Syndrome: Diagnosis, Dental Management, and a Case Report.Case reports in dentistry · 2019Article
- The status ofMedical journal of the Islamic Republic of Iran · 2019Article
- Consanguineous marriages in the genetic counseling centers of Isfahan and the ethical issues of clinical consultations.Journal of medical ethics and history of medicine · 2017Article
- The genetic background of Southern Iranian couples before marriage.Balkan journal of medical genetics : BJMG · 2016Article
- Consanguineous marriages : Preconception consultation in primary health care settings.Journal of community genetics · 2012Article
- Mutation analysis of the CYP21A2 gene in the Iranian population.Genetic testing and molecular biomarkers · 2012Article
- Is there a significant trend in prevalence of consanguineous marriage in Tehran? A review of three generations.Journal of genetic counseling · 2009Article
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Population based genetic counseling that promotes public health goals is an appropriate health care service. The genetic counseling center in Shiraz, southern Iran serves most of the clients in the region. During a 4-year period, 2,686 couples presented for genetic counseling. Data files revealed that 85% had consanguineous relationships (1.5% double first cousin, 74% first cousin, 8% second cousin, 1.5% beyond second cousin). Most prevalent reasons for referral were premarital counseling (80%), with 89% consanguinity, followed by preconception (12%), postnatal (7%), and prenatal counseling (1%). The most common abnormalities in probands or relatives were intellectual and developmental disabilities, hearing loss/impairment, and neuromuscular dystrophies. Family history of medical problem(s) and/or consanguinity was the main indication for referral in nearly every family. Premarital consanguinity poses unique challenges and opportunities. There is considerable opportunity for genetic counseling and education for couples in this population. The tradition of consanguinity, which is likely to persist in Iran, requires multidisciplinary agreement regarding the appropriate process of genetic counseling. Effective genetic counseling in Iran hinges on inclusion of data from genetic counseling services in national genomic and epidemiologic research programs.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.