ArticleNeuroscience letters2008
Characterization of trkB immunoreactive cells in the intermediolateral cell column of the rat spinal cord.
Article in Neuroscience letters, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 9 citations in OpenAlex.
- Retrograde influences of SCG axotomy on uninjured preganglionic neurons.Brain research · 2018Article
- Increased Cx32 expression in spinal cord TrkB oligodendrocytes following peripheral axon injury.Neuroscience letters · 2016Article
- Distribution and phenotype of TrkB oligodendrocyte lineage cells in the adult rat spinal cord.Brain research · 2014Article
- Transection of preganglionic axons leads to CNS neuronal plasticity followed by survival and target reinnervation.Autonomic neuroscience : basic & clinical · 2013Article
- Transient changes in spinal cord glial cells following transection of preganglionic sympathetic axons.Autonomic neuroscience : basic & clinical · 2012Article
- Characterization of trkB immunoreactive cells in the intermediolateral cell column of the rat spinal cord.Neuroscience letters · 2008Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
The objective of the present study was to characterize the trkB receptor immunoreactive (-ir) cells in the intermediolateral cell column (IML) of the upper thoracic spinal cord. Small trkB-ir cells (area=56.1+/-4.4 microm(2)) observed in the IML showed characteristics of oligodendrocytes and were frequently observed in close apposition to choline acetyltransferase (ChAT)-ir cell bodies. Large trkB-ir cells (area=209.3+/-25.2 microm(2)) showed immunoreactivity for the neuronal marker NeuN, indicating their neuronal phenotype, as well as for ChAT, a marker for preganglionic neurons. TrkB and ChAT were co-localized in IML neurons primarily in cases that had received in vivo administration of nerve growth factor (NGF). These findings reveal two different cell types, oligodendrocytes and neurons, in the IML of the spinal cord that show trkB immunoreactivity, suggesting their regulation by brain derived neurotrophic factor (BDNF) and/or neurotrophin-4 (NT-4). In addition, there is evidence that NGF may play a role in the regulation of trkB-ir preganglionic neurons in the IML.
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Registered trials
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