ArticleBiological psychiatry2008
The social-emotional processing stream: five core constructs and their translational potential for schizophrenia and beyond.
Article in Biological psychiatry, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 136 papers, 4 of them syntheses that pooled it.
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Who cites it
136 citing papers in PubMed, 4 syntheses or guidelines pooled it, 294 citations in OpenAlex.
- Subspecialization in the human posterior medial cortex.NeuroImage · 2015Pooled it
- Symptom domains and neurocognitive functioning can help differentiate social cognitive processes in schizophrenia: a meta-analysis.Schizophrenia bulletin · 2013Pooled it
- Meta-analysis of functional neuroimaging studies of emotion perception and experience in schizophrenia.Biological psychiatry · 2012Pooled it
- Pooled it
- A 12-week randomized controlled trial of twice-daily intranasal oxytocin for social cognitive deficits in people with schizophrenia.Schizophrenia research · 2017Trial
- Study protocol: a randomised controlled trial of cognitive remediation for a national cohort of forensic mental health patients with schizophrenia or schizoaffective disorder.BMC psychiatry · 2016Trial
- Trial
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- Neural Correlates of Emotion Regulation and Associations With Disordered Eating During Preadolescence.Developmental psychobiology · 2025Article
- The first study of a mentalizing mediator model in a community sample of nonsuicidal self-injured adolescents and its association with salivary oxytocin.Frontiers in psychiatry · 2025Article
- Effects of intranasal oxytocin on cigarette withdrawal and smoking in the laboratory: Differences by sex and social functioning traits.Experimental and clinical psychopharmacology · 2024Article
- Two Sides of Theory of Mind: Mental State Attribution to Moving Shapes in Paranoid Schizophrenia Is Independent of the Severity of Positive Symptoms.Brain sciences · 2024Article
- Functional magnetic resonance imaging in schizophrenia: current evidence, methodological advances, limitations and future directions.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Pilot study on the effectiveness of the socialmind program for the rehabilitation of social cognition following acquired brain injury.Frontiers in psychology · 2024Article
- Social cognition and emotional rehabilitation in participants with schizofrenia.Frontiers in psychiatry · 2023Article
76 more citing papers are in PubMed but not listed here.
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Abstract
backgroundCognitive neuroscience approaches to translational research have made great strides toward understanding basic mechanisms of dysfunction and their relation to cognitive deficits, such as thought disorder in schizophrenia. The recent emergence of Social Cognitive and Affective Neuroscience has paved the way for similar progress to be made in explaining the mechanisms underlying the social and emotional dysfunctions (i.e., negative symptoms) of schizophrenia and that characterize virtually all DSM Axis I and II disorders more broadly.
methodsThis article aims to provide a roadmap for this work by distilling from the emerging literature on the neural bases of social and emotional abilities a set of key constructs that can be used to generate questions about the mechanisms of clinical dysfunction in general and schizophrenia in particular.
resultsTo achieve these aims, the first part of this article sketches a framework of five constructs that comprise a social-emotional processing stream. The second part considers how future basic research might flesh out this framework and translational work might relate it to schizophrenia and other clinical populations.
conclusionsAlthough the review suggests there is more basic research needed for each construct, two in particular--one involving the bottom-up recognition of social and emotional cues, the second involving the use of top-down processes to draw mental state inferences--are most ready for translational work.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.