Trial reportActa paediatrica (Oslo, Norway : 1992)2008
Nasal high-frequency ventilation for premature infants.
Trial report in Acta paediatrica (Oslo, Norway : 1992), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 19 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Nasal High Frequency Oscillatory Versus Nasal Intermittent Positive Pressure Ventilation in Neonate After Extubation
Nasal HFOV vs Nasal CPAP: Effects on Gas Exchange for the Treatment of Neonates Recovering From Respiratory Distress Syndrome. A Multicenter Randomized Controlled Trial
Who cites it
19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 89 citations in OpenAlex.
- Non-invasive high-frequency ventilation in newborn infants with respiratory distress.The Cochrane database of systematic reviews · 2024Pooled it
- Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials.Respiratory research · 2019Pooled it
- The effect of non-invasive high-frequency oscillatory ventilation on the duration of non-invasive respiratory support in late preterm and term infants with transient tachypnea of the newborn: a randomized controlled trial.European journal of pediatrics · 2023Trial
- Non-invasive high-frequency oscillatory ventilation in preterm infants after extubation: a randomized, controlled trial.The Journal of international medical research · 2021Trial
- Hazards to avoid in future neonatal studies of nasal high-frequency oscillatory ventilation: lessons from an early terminated trial.BMC research notes · 2019Trial
- Non-invasive high-frequency ventilation versus bi-phasic continuous positive airway pressure (BP-CPAP) following CPAP failure in infants <1250 g: a pilot randomized controlled trial.Journal of perinatology : official journal of the California Perinatal Association · 2017Trial
- Nasal High-Frequency Oscillatory Ventilation Use in Romanian Neonatal Intensive Care Units-The Results of a Recent Survey.Children (Basel, Switzerland) · 2024Article
- A Review on Non-invasive Respiratory Support for Management of Respiratory Distress in Extremely Preterm Infants.Frontiers in pediatrics · 2020Review
- Article
- Response to 'Non-invasive high frequency ventilation and the errors from the past: designing simple trials neglecting complex respiratory physiology'.Journal of perinatology : official journal of the California Perinatal Association · 2017Article
- [Research advances in noninvasive high-frequency oscillatory ventilation in neonates].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017Review
- High-frequency ventilation for non-invasive respiratory support of neonates.Seminars in fetal & neonatal medicine · 2016Review
- Nasal HFOV with Binasal Cannula Appears Effective and Feasible in ELBW Newborns.Journal of tropical pediatrics · 2016Article
- Nasal high-frequency oscillation ventilation in neonates: a survey in five European countries.European journal of pediatrics · 2015Article
- The role of surfactant and non-invasive mechanical ventilation in early management of respiratory distress syndrome in premature infants.World journal of pediatrics : WJP · 2014Review
- High-frequency nasal ventilation for 21 d maintains gas exchange with lower respiratory pressures and promotes alveolarization in preterm lambs.Pediatric research · 2014Article
- Non-invasive Ventilation in Premature Infants: Based on Evidence or Habit.Journal of clinical neonatology · 2013Review
- Comparison of patient-ventilator interfaces based on their computerized effective dead space.Intensive care medicine · 2011Article
- Noninvasive high frequency oscillatory ventilation through nasal prongs: bench evaluation of efficacy and mechanics.Intensive care medicine · 2010Article
Corrections and comments
- Commented on by
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
aimTo assess the use of nasal high-frequency ventilation (HFV) to provide noninvasive ventilatory support for very low birthweight (VLBW) infants. STUDY
designVLBW infants, >7 days of age on nasal continuous positive airway pressure (CPAP), were placed on nasal HFV for 2 h using the Infant Star high-frequency ventilator (Mallinckrodt, Inc., St. Louis, MO, USA). Mean airway pressure was set to equal the previous level of CPAP, and amplitude was adjusted to obtain chest wall vibration. Capillary blood was sampled before starting HFV and after 2 h to determine change in pH and partial pressure of carbon dioxide (pCO(2)).
resultsFourteen subjects were studied, 10 males and 4 females. Gestational age was 26-30 weeks (median 27). Age at study was 18-147 days (median 30). Median birth weight was 955 g; median weight at study was 1605 g. Nasal CPAP pressure was 4-7 cm H(2)O (mean 5). Amplitude was 30-60 (median 50). After 2 h, PCO(2) (mean 45 torr) was significantly lower than initial PCO(2) (mean 50 torr) (p = 0.01), and pH had increased significantly (7.40 vs. 7.37, p = 0.04).
conclusionsNasal HFV is effective in decreasing pCO(2) in stable premature infants requiring nasal CPAP support. Long-term use of nasal HFV requires further study.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.