ArticlePediatric nephrology (Berlin, Germany)2008
The spectrum of chronic kidney disease (stages 2-5) in KwaZulu-Natal, South Africa.
Article in Pediatric nephrology (Berlin, Germany), 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Kidney disease among children in sub-Saharan Africa: systematic review.Pediatric research · 2015Pooled it
- Chronic kidney disease (stages 3-5) in children at Chris Hani Baragwanath Academic Hospital, 2000-2019.BMC nephrology · 2026Article
- Catastrophic healthcare expenditure and caregiver burden in pediatric chronic kidney disease - a mixed methods study from a low resource setting.Pediatric nephrology (Berlin, Germany) · 2024Article
- Kidney transplantation in low- and middle-income countries: the Transplant Links experience.Pediatric nephrology (Berlin, Germany) · 2024Review
- Spectrum of congenital anomalies of the kidney and urinary tract in a pediatric nephrology clinic in Ethiopia and factors associated with advanced chronic kidney disease: A cross-sectional study.PLOS global public health · 2024Article
- Hiding in plain sight: genetics of childhood steroid-resistant nephrotic syndrome in Sub-Saharan Africa.Pediatric nephrology (Berlin, Germany) · 2023Review
- Burden of Paediatric Kidney Diseases in a Tertiary Care Hospital in Harare, Zimbabwe.Clinical medicine insights. Pediatrics · 2023Article
- Paediatric Nephrology in Africa.Current pediatrics reports · 2021Review
- Risk Factors for Progression of Chronic Kidney Disease With Glomerular Etiology in Hospitalized Children.Frontiers in pediatrics · 2021Article
- Ethnic prevalence of anemia and predictors of anemia among chronic kidney disease patients at a tertiary hospital in Johannesburg, South Africa.International journal of nephrology and renovascular disease · 2019Article
- Risk factors and co-morbidities associated with changes in renal function among antiretroviral treatment-naïve adults in South Africa: A chart review.Southern African journal of HIV medicine · 2018Article
- Arginine dimethylation products in pediatric patients with chronic kidney disease.Annals of medicine and surgery (2012) · 2016Article
- Paediatric end-stage renal disease in a tertiary hospital in South West Nigeria.BMC nephrology · 2014Article
- Nephrology in Africa--not yet uhuru.Nature reviews. Nephrology · 2013Review
- Epidemiology of chronic kidney disease in children.Pediatric nephrology (Berlin, Germany) · 2012Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The burden of chronic kidney disease (CKD) in children in developing countries remains unknown, due to the lack of a national data-reporting system. We undertook a retrospective study of all children < 16 years old in our hospital, which is the tertiary referral centre for children with complex kidney disorders, to analyse the spectrum of CKD (stages 2-5) from 1994-2006. Six hundred and fifty-three children with kidney disorders were screened for CKD; 286 (44.0%) were < 5 years old. Of these, 177 (62%) were male, 202 (70.6%) were black, 77 (26.9%) were Indian, five (1.8%) were mixed race and two (0.7%) were white. One hundred and twenty-six children had CKD (stages 2-5); 55 (43.7%) were < 5 years olds; 41 (74.5%) were male. There were 71 (56.3%) that were > 5 years old, 42 (59.2%) were male. The commonest cause of CKD (stages 2-5) in all children was nephrotic syndrome, comprising 30.9% in children < 5 years old and 40.8% in children > 5 years old. Within the observation period of 11 years, end-stage kidney disease was diagnosed in 20 children; only nine had been on long-term dialysis, and seven qualified for transplantation. Five (25%) children had died, four from sepsis during dialysis and one from tuberculosis after receiving a transplant. We concluded that lack of resources, late referrals, and high cost of renal replacement therapy in developing countries leads to poor outcome in CKD.
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