ArticleThe Canadian journal of cardiology2008
Trends in antihypertensive drug prescriptions and physician visits in Canada between 1996 and 2006.
Article in The Canadian journal of cardiology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Trial
- Printed educational messages fail to increase use of thiazides as first-line medication for hypertension in primary care: a cluster randomized controlled trial [ISRCTN72772651].Implementation science : IS · 2016Trial
- Combination therapy as initial treatment for newly diagnosed hypertension.American heart journal · 2011Trial
- Prescription Trends of Thiazide Diuretics in a Canadian Primary Care Population From 2015 to 2021.CJC open · 2024Article
- Differences in Antihypertensive Medication Prescription Profiles Between 2009 and 2021: A Retrospective Cohort Study of CARTaGENE.Canadian journal of kidney health and disease · 2024Article
- Article
- ACSC Indicator: testing reliability for hypertension.BMC medical informatics and decision making · 2017Article
- Isometric Handgrip as an Adjunct for Blood Pressure Control: a Primer for Clinicians.Current hypertension reports · 2017Review
- Comparison of the Effect of Thiazide Diuretics and Other Antihypertensive Drugs on Central Blood Pressure: Cross-Sectional Analysis Among Nondiabetic Patients.Journal of clinical hypertension (Greenwich, Conn.) · 2015Article
- Old habits die hard: a nationwide utilization study of short-acting nifedipine in Taiwan.PloS one · 2014Article
- Benefits and pitfalls of cardiovascular medication in seniors.Wiener klinische Wochenschrift · 2013Review
- New prescriptions of spironolactone associated with angiotensin-converting-enzyme inhibitors and/or angiotensin receptor blockers and their laboratory monitoring from 2001 to 2008: a population study on older people living in the community in Italy.European journal of clinical pharmacology · 2013Article
- What differentiates primary care physicians who predominantly prescribe diuretics for treating mild to moderate hypertension from those who do not? A comparative qualitative study.BMC family practice · 2012Article
- Harmonization of guidelines for the prevention and treatment of cardiovascular disease: the C-CHANGE Initiative.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2011Article
- Hypertension and type 2 diabetes: what family physicians can do to improve control of blood pressure--an observational study.BMC family practice · 2011Article
- Article
- Do recommendations for the management of hypertension improve cardiovascular outcome? The canadian experience.International journal of hypertension · 2011Article
- Regional variations in not treating diagnosed hypertension in Canada.The Canadian journal of cardiology · 2010Article
- 2010 Canadian Hypertension Education Program recommendations: An annual update.Canadian family physician Medecin de famille canadien · 2010Article
- 2010 Canadian Hypertension Education Program (CHEP) recommendations: the scientific summary - an update of the 2010 theme and the science behind new CHEP recommendations.The Canadian journal of cardiology · 2010Review
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIn 1999, the Canadian Hypertension Education Program (CHEP) was launched to develop and implement evidence-based hypertension guidelines.
objectivesTo determine temporal trends in antihypertensive drug prescribing and physician visits for hypertension in Canada, and correlate these trends with CHEP recommendations.
methodsLongitudinal drug data (Intercontinental Medical Statistics [IMS] CompuScript database; IMS Health Canada) were used to examine prescriptions over an 11-year period (1996 to 2006) for five major cardiovascular drug classes. The IMS Canadian Disease and Therapeutic Index database was used to determine trends in physician office visits for hypertension.
resultsPrescriptions for antihypertensive agents increased significantly over the 11-year period (4054% for angiotensin receptor blockers, 127% for thiazide diuretics, 108% for angiotensin-converting enzyme inhibitors, 87% for beta-blockers and 55% for calcium channel blockers). Time series analyses demonstrated increases in the growth rate for all drug classes, with the greatest annual change in prescriptions occurring during the 1999 to 2002 time period (except in angiotensin receptor blockers). An increase in prescriptions for fixed-dose combination products occurred, which was temporally related to the change in CHEP recommendations encouraging their use in 2001. The proportion of physician office visits for hypertension increased significantly from 4.9% in 1995 to 6.8% in 2005 (P<0.001).
conclusionsThe largest increase in antihypertensive drug prescribing occurred in the period immediately following implementation of CHEP (1999 to 2002). Although prescribing rates are still increasing, the rate of change has decreased, suggesting that the treatment market for hypertension may be becoming saturated. The impact of these changes on blood pressure control and clinical outcomes remains to be determined.
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