Evidence map›Paper›PMID 18546335›Full record

ReviewBirth defects research. Part C, Embryo today : reviews2008

Cell biology of embryonic migration.

Satoshi Kurosaka, Anna Kashina

Abstract readReview
In one paragraph

Review in Birth defects research. Part C, Embryo today : reviews, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed.

  1. Article
  2. A Mathematical Model for Chemo-Mechanically Induced Collective Cell Motility on Planar Elastic Substrates.International journal for numerical methods in biomedical engineering · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Plasticity in leukocyte migration during haematopoiesis and inflammation.Journal of muscle research and cell motility · 2025
    Review
  9. FAK Differentially Mechanoregulates Cell Migration During Wound Closure.bioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Emergence of Ectopic Adrenal Tissues-What are the Probable Mechanisms?Journal of clinical research in pediatric endocrinology · 2022
    Review
  16. A primer to traction force microscopy.The Journal of biological chemistry · 2022
    Review
  17. Article
  18. Review
  19. Article
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Satoshi KurosakaDepartment of Animal Biology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
Anna Kashina

Funding

Role of Protein Arginylation in Cardiovascular DevelopmentR01HL084419 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI KASHINA, ANNA S · 2007 to 2011
$2.2M
NHLBI NIH HHS 5R01HL084419-01 A1NHLBI NIH HHS R01 HL084419
6 · The paper itself

Abstract

Cell migration is an evolutionarily conserved mechanism that underlies the development and functioning of uni- and multicellular organisms and takes place in normal and pathogenic processes, including various events of embryogenesis, wound healing, immune response, cancer metastases, and angiogenesis. Despite the differences in the cell types that take part in different migratory events, it is believed that all of these migrations occur by similar molecular mechanisms, whose major components have been functionally conserved in evolution and whose perturbation leads to severe developmental defects. These mechanisms involve intricate cytoskeleton-based molecular machines that can sense the environment, respond to signals, and modulate the entire cell behavior. A big question that has concerned the researchers for decades relates to the coordination of cell migration in situ and its relation to the intracellular aspects of the cell migratory mechanisms. Traditionally, this question has been addressed by researchers that considered the intra- and extracellular mechanisms driving migration in separate sets of studies. As more data accumulate researchers are now able to integrate all of the available information and consider the intracellular mechanisms of cell migration in the context of the developing organisms that contain additional levels of complexity provided by extracellular regulation. This review provides a broad summary of the existing and emerging data in the cell and developmental biology fields regarding cell migration during development.

Indexed as

AnimalsBrainCell AdhesionCell MovementCytoskeletonEmbryo, MammalianEmbryonic DevelopmentEmbryo, NonmammalianGerm CellsHeartHumansMesodermModels, BiologicalMovementNeural CrestProtein Processing, Post-Translational

Identifiers

PMID18546335
PMCPMC2542983

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.