Evidence map›Paper›PMID 18546011›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2008

Emulsification and inverted hypopyon formation of oxane HD in the anterior chamber.

Wico W Lai, David Wong, Kenneth K Li, Po-lin Leow

Abstract readCase Reports
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In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Long-term outcomes of Oxane Hd as intraocular tamponade in the treatment of complicated retinal detachment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2010
    Trial
  3. Article
  4. Vitreous Substitutes as Drug Release Systems.Translational vision science & technology · 2022
    Review
  5. Article
  6. Article
  7. Article
  8. Quantifying silicone oil emulsification in patients: are we only seeing the tip of the iceberg?Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2015
    Article
  9. Vitreous substitutes: the present and the future.BioMed research international · 2014
    Review
  10. Retrospective review of 50 eyes with long-term silicone oil tamponade for more than 12 months.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2012
    Article
  11. In vitro emulsification assessment of new silicone oils.The British journal of ophthalmology · 2010
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Wico W LaiDepartment of Ophthalmology, Queen Mary Hospital, Pokfulam, Hong Kong, People's Republic of China. wicolai@hku.hk
David Wong
Kenneth K Li
Po-lin Leow
Queen Mary Hospital · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOxane HD(R) is a "heavier-than-water" silicone oil which has a specific gravity of 1.02 g/cm(3). When dispersed into droplets, one expects them to sink. We report a case of emulsification of Oxane HD in an eye that unexpectedly manifested as an "inverted hypopyon".

methodsThe clinical findings of a 45-year-old man who underwent pars plana vitrectomy and Oxane HD endotamponade for a phakic inferior rhegmatogenous retinal detachment are described.

resultsA large silicone oil globule was noted to be floating in the anterior chamber on postoperative day 1. Emulsification of the globule and inverted hypopyon formation were subsequently observed at 2 months postoperatively.

conclusionsEmulsification and inverted hypopyon formation in the anterior chamber may occur with Oxane HD. One explanation might be that the Oxane HD has separated out into its constituent components of silicone and RMN3, which raises questions as to the basis for its claim to be a heavier-than-water tamponade.

Indexed as

VitrectomyAnterior ChamberEmulsionsHumansInjectionsMaleMiddle AgedPostoperative ComplicationsRetinal DetachmentRetinal PerforationsSilicone OilsVitreous BodyEmulsionsoxane HDSilicone Oils

Identifiers

PMID18546011
OpenAlexW2064433906

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.