Evidence map›Paper›PMID 18545882›Full record

ArticleTechniques in coloproctology2008

Anastomotic leaks after anterior resection for mid and low rectal cancer: survey of the Italian Society of Colorectal Surgery.

C R Asteria, G Gagliardi, S Pucciarelli, G Romano, A Infantino, F La Torre, F Tonelli, F Martin, C Pulica, V Ripetti and 19 more

Open access · greenAbstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Techniques in coloproctology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
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  11. Article
  12. The Role of Temporary Fecal Diversion.Clinics in colon and rectal surgery · 2017
    Review
  13. Review
  14. Article
  15. Article
  16. Obesity and colorectal cancer.Clinics in colon and rectal surgery · 2011
    Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

29 authors at 18 institutions in 2 countries.

C R AsteriaDepartment of Clinical Physiopathology AOU Careggi, University of Florence, Via Morgagni 85, I-50134 Florence, Italy. corrado.asteria@libero.it
G Gagliardi
S Pucciarelli
G Romano
A Infantino
F La Torre
F Tonelli
F Martin
C Pulica
V Ripetti
G Diana
G Amicucci
M Carlini
A Sommariva
G Vinciguerra
D B Poddie
A Amato
R Bassi
R Galleano
E Veronese
S Mancini
G Pescio
G L Occelli
S Bracchitta
M Castagnola
T Pontillo
G Cimmino
U Prati
R Vincenti
Ospedale Civile Di Ivrea · ITSapienza University of Rome · ITAzienda Ospedaliera Carlo Poma · ITAzienda Ospedaliero-Universitaria Careggi · ITClinica Mediterranea · ITIstituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITIstituto Oncologico Veneto · ITNordland Hospital · NONuovo Ospedale San Giovanni di Dio · ITOspedale Buon Consiglio Fatebenefratelli · ITOspedale Cannizzaro · ITOspedale Madonna Delle Grazie · ITOspedale Maggiore · ITSt. Eugenio Hospital · ITUniversity of Florence · ITUniversity of L'Aquila · ITUniversity of Padua · ITUniversity of Palermo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe aim of the survey was to assess the incidence of anastomotic leaks (AL) and to identify risk factors predicting incidence and gravity of AL after low anterior resection (LAR) for rectal cancer performed by colorectal surgeons of the Italian Society of Colorectal Surgery (SICCR).

methodsInformation about patients with rectal cancers less than 12 cm from the anal verge who underwent LAR during 2005 was collected retrospectively. AL was classified as grade I to IV according to gravity. Fifteen clinical variables were examined by univariate and multivariate analyses. Further analysis was conducted on patients with AL to identify factors correlated with gravity.

resultsThere were 520 patients representing 64% of LAR for rectal cancer performed by SICCR members. The overall rate of AL was 15.2%. Mortality was 2.7% including 0.6% from AL. The incidence of AL was correlated with higher age (p<0.05), lower (<20 per year) centre case volume (p<0.05), obesity (p<0.05), malnutrition (p<0.01) and intraoperative contamination (p<0.05), and was lower in patients with a colonic J-pouch reservoir (p<0.05). In the multivariate analysis age, malnutrition and intraoperative contamination were independent predictors. The only predictor of severe (grade III/IV) AL was alcohol/smoking habits (p<0.05) while the absence of a diverting stoma was borderline significant (p<0.07).

conclusionOur retrospective survey identified several risk factors for AL. This survey was a necessary step to construct prospective interventional studies and to establish benchmark standards for outcome studies.

Indexed as

AgedAnastomosis, SurgicalChi-Square DistributionFemaleHumansIncidenceItalyLogistic ModelsMaleMiddle AgedPostoperative ComplicationsRectal NeoplasmsRetrospective StudiesRisk FactorsTreatment Outcome

Identifiers

PMID18545882
OpenAlexW2031268194

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.