Evidence map›Paper›PMID 18544168›Full record

Trial reportBMC family practice2008

CRISTOPH - a cluster-randomised intervention study to optimise the treatment of patients with hypertension in General Practice.

Achim Mortsiefer, Tobias Meysen, Martin Schumacher, Claudia Lintges, Maren Stamer, Norbert Schmacke, Karl Wegscheider, Heinz-Harald Abholz, Jürgen In der Schmitten

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC family practice, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Achim MortsieferDepartment of General Practice, University Hospital, P,O, Box 101001, 40225 Düsseldorf, Germany. achim.mortsiefer@med.uni-duesseldorf.de
Tobias Meysen
Martin Schumacher
Claudia Lintges
Maren Stamer
Norbert Schmacke
Karl Wegscheider
Heinz-Harald Abholz
Jürgen In der Schmitten
Düsseldorf University Hospital · DEHeinrich Heine University Düsseldorf · DEStaats- und Universitätsbibliothek Bremen · DEUniversität Hamburg · DEUniversity of Bremen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent guidelines for the management of hypertension focus on treating patients according to their global cardiovascular risk (CVR), rather than strictly keeping blood pressure, or other risk factors, below set limit values. The objective of this study is to compare the effect of a simple versus a complex educational intervention implementing this new concept among General Practitioners (GPs). METHODS/

designA prospective longitudinal cluster-randomised intervention trial with 94 German GPs consecutively enroling 40 patients each with known hypertension. All GPs then received a written manual specifically developed to transfer the global concept of CVR into daily General Practice. After cluster-randomisation, half of the GPs additionally received a clinical outreach visit, with a trained peer discussing with them the concept of global CVR referring to example study patients from the respective GP. Main outcome measure is the improvement of calculated CVR six months after intervention in the subgroup of patients with high CVR (but no history of cardiovascular disease), defined as 10-year-mortality > or = 5% employing the European SCORE formula. Secondary outcome measures include the intervention's effect on single risk factors, and on prescription rates of drugs targeting CVR. All outcome measures are separately studied in the three subgroups of patients with 1. high CVR (defined as above), 2. low CVR (SCORE < 5%), and 3. a history of cardiovascular disease. The influence of age, sex, social status, and the perceived quality of the respective doctor-patient-relation on the effects will be examined. DISCUSSION: To our knowledge, no other published intervention study has yet evaluated the impact of educating GPs with the goal to treat patients with hypertension according to their global cardiovascular risk.

trial registrationISRCTN44478543.

Indexed as

Cardiovascular DiseasesFamily PracticeGuideline AdherencePractice Guidelines as TopicAdultAgedData CollectionFemaleGermanyHumansHypertensionLongitudinal StudiesMaleMiddle AgedPatient DropoutsPhysicians, Family

Identifiers

PMID18544168
PMCPMC2459168
OpenAlexW2088340222

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.