ArticleTAG. Theoretical and applied genetics. Theoretische und angewandte Genetik2008
Exploiting regulatory variation to identify genes underlying quantitative resistance to the wheat stem rust pathogen Puccinia graminis f. sp. tritici in barley.
Article in TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed, 51 citations in OpenAlex.
- Molecular mechanisms underpinning quantitative resistance toFrontiers in plant science · 2023Article
- Genomic basis of white pine blister rust quantitative disease resistance and its relationship with qualitative resistance.The Plant journal : for cell and molecular biology · 2020Article
- Transcriptomic and presence/absence variation in the barley genome assessed from multi-tissue mRNA sequencing and their power to predict phenotypic traits.BMC genomics · 2019Article
- Transposable element insertions shape gene regulation and melanin production in a fungal pathogen of wheat.BMC biology · 2018Article
- Time-course expression QTL-atlas of the global transcriptional response of wheat to Fusarium graminearum.Plant biotechnology journal · 2017Article
- Quantitative Resistance: More Than Just Perception of a Pathogen.The Plant cell · 2017Review
- Major Novel QTL for Resistance to Cassava Bacterial Blight Identified through a Multi-Environmental Analysis.Frontiers in plant science · 2017Article
- Prior knowledge guided eQTL mapping for identifying candidate genes.BMC bioinformatics · 2016Article
- The Quantitative Basis of the Arabidopsis Innate Immune System to Endemic Pathogens Depends on Pathogen Genetics.PLoS genetics · 2016Article
- Genome-Editing Technologies for Enhancing Plant Disease Resistance.Frontiers in plant science · 2016Review
- Expression quantitative trait loci infer the regulation of isoflavone accumulation in soybean (Glycine max L. Merr.) seed.BMC genomics · 2014Article
- Genetical and comparative genomics of Brassica under altered Ca supply identifies Arabidopsis Ca-transporter orthologs.The Plant cell · 2014Article
- Prospects for advancing defense to cereal rusts through genetical genomics.Frontiers in plant science · 2013Article
- Genetic dissection of growth, wood basic density and gene expression in interspecific backcrosses of Eucalyptus grandis and E. urophylla.BMC genetics · 2012Article
- cDNA-AFLP-based genetical genomics in cotton fibers.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2012Article
- Quantitative and qualitative stem rust resistance factors in barley are associated with transcriptional suppression of defense regulons.PLoS genetics · 2011Article
- Regulatory hotspots are associated with plant gene expression under varying soil phosphorus supply in Brassica rapa.Plant physiology · 2011Article
- Expression level of a gibberellin 20-oxidase gene is associated with multiple agronomic and quality traits in barley.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2011Article
- Differential gene expression in nearly isogenic lines with QTL for partial resistance to Puccinia hordei in barley.BMC genomics · 2010Article
- Data-driven assessment of eQTL mapping methods.BMC genomics · 2010Article
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Authors and funding
14 authors at 7 institutions in 2 countries.
Funding
Abstract
We previously mapped mRNA transcript abundance traits (expression-QTL or eQTL) using the Barley1 Affymetrix array and 'whole plant' tissue from 139 progeny of the Steptoe x Morex (St/Mx) reference barley mapping population. Of the 22,840 probesets (genes) on the array, 15,987 reported transcript abundance signals that were suitable for eQTL analysis, and this revealed a genome-wide distribution of 23,738 significant eQTLs. Here we have explored the potential of using these mRNA abundance eQTL traits as surrogates for the identification of candidate genes underlying the interaction between barley and the wheat stem rust fungus Puccinia graminis f. sp. tritici. We re-analysed quantitative 'resistance phenotype' data collected on this population in 1990/1991 and identified six loci associated with barley's reaction to stem rust. One of these coincided with the major stem rust resistance locus Rpg1, that we had previously positionally cloned using this population. Correlation analysis between phenotype values for rust infection and mRNA abundance values reported by the 22,840 GeneChip probe sets placed Rpg1, which is on the Barley1 GeneChip, in the top five candidate genes for the major QTL on chromosome 7H corresponding to the location of Rpg1. A second co-located with the rpg4/Rpg5 stem rust resistance locus that has been mapped in a different population and the remaining four were novel. Correlation analyses identified candidate genes for the rpg4/Rpg5 locus on chromosome 5H. By combining our data with additional published mRNA profiling data sets, we identify a putative sensory transduction histidine kinase as a strong candidate for a novel resistance locus on chromosome 2H and compile candidate gene lists for the other three loci.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.