ReviewPsychosomatic medicine2008
Effects of psychological interventions on neuroendocrine hormone regulation and immune status in HIV-positive persons: a review of randomized controlled trials.
Review in Psychosomatic medicine, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Non-specialist psychosocial support interventions for women living with HIV: A systematic review.AIDS care · 2017Pooled it
- Depression treatment enhances adherence to antiretroviral therapy: a meta-analysis.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2014Pooled it
- Depression and HIV/AIDS treatment nonadherence: a review and meta-analysis.Journal of acquired immune deficiency syndromes (1999) · 2011Pooled it
- A Feasibility Study to Develop and Test a Cognitive Behavioral Stress Management Mobile Health Application for HIV-Related Fatigue.Journal of pain and symptom management · 2020Trial
- Trial
- A pilot study of cognitive behavioral stress management effects on stress, quality of life, and symptoms in persons with chronic fatigue syndrome.Journal of psychosomatic research · 2011Trial
- HIV-1 clade C infection and progressive disruption in the relationship between cortisol, DHEAS and CD4 cell numbers: a two-year follow-up study.Clinica chimica acta; international journal of clinical chemistry · 2009Trial
- Randomized controlled trial of a cognitive-behavioral intervention for HIV-positive persons: an investigation of treatment effects on psychosocial adjustment.AIDS and behavior · 2009Trial
- A behavioral intervention reduces HIV transmission risk by promoting sustained serosorting practices among HIV-infected men who have sex with men.Journal of acquired immune deficiency syndromes (1999) · 2008Trial
- Study protocol: an observational study of distress, immune function and persistent pain in HIV.BMJ open · 2022Article
- Effects of Open-Label Placebos on State Anxiety and Glucocorticoid Stress Responses.Brain sciences · 2021Article
- Modulation of Phenylalanine and Tyrosine Metabolism in HIV-1 Infected Patients with Neurocognitive Impairment: Results from a Clinical Trial.Metabolites · 2020Article
- A novel technology-enhanced internalized stigma and shame intervention for HIV-positive persons with substance use disorders.Cognitive and behavioral practice · 2020Article
- The Symptoms Self-Management Center (SSMC): Methods for developing and implementing technology-enhanced self-management interventions for pain and fatigue.Applied nursing research : ANR · 2019Article
- Article
- Psychosocial risk and management of physical diseases.Journal of behavioral medicine · 2019Review
- Peer victimization and diurnal cortisol rhythm among children affected by parental HIV: Mediating effects of emotional regulation and gender differences.Psychoneuroendocrinology · 2018Article
- Psychosocial and behavioural interventions towards HIV risk reduction for serodiscordant couples in Africa: A systematic review.The South African journal of psychiatry : SAJP : the journal of the Society of Psychiatrists of South Africa · 2018Article
- Change in urinary cortisol excretion mediates the effect of angry/hostile mood on 9 month diastolic blood pressure in HIV+ adults.Journal of behavioral medicine · 2017Article
- β-Adrenergic-stimulated macrophages: Comprehensive localization in the M1-M2 spectrum.Brain, behavior, and immunity · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
We reviewed randomized controlled trials (RCTs) that examined the effects of psychological interventions on HIV disease markers including neuroendocrine hormone regulation and immune status. Utilizing both PubMed and PsycINFO, we searched for RCTs published over the past 20 years (1987-2007). Of the 31 RCTs identified, 14 tested effects of psychological interventions on neuroendocrine regulation or immune status. Despite the fact that there are significant methodological limitations of RCTs that have been conducted to date, psychological interventions for HIV-positive persons have been shown to be efficacious in improving psychological adjustment compared with wait-list or treatment as usual control conditions. However, there is little support for differential efficacy of group-based interventions that have been tested to date, even in comparison with semistructured social support groups. Irrespective of the treatment modality, it seems that interventions that are successful in improving psychological adjustment are more likely to have salutary effects on neuroendocrine regulation and immune status. Psychological interventions represent a viable adjuvant treatment that can assist patients with improving psychological adjustment and potentially enhancing immune status. To inform the development of innovative treatments with potentially superior efficacy, deconstruction trials are necessary to examine the effects of distinct components of multimodal psychological interventions compared with nonspecific social support effects. Effectiveness trials of promising psychological interventions with more representative samples of HIV-positive persons are also needed to provide more definitive information on the clinical utility and potential cost-effectiveness of treatments that have been developed to date.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.