Evidence map›Paper›PMID 18541573›Full record

ArticleThe American journal of clinical nutrition2008

Gestational weight gain and risk of overweight in the offspring at age 7 y in a multicenter, multiethnic cohort study.

Brian H Wrotniak, Justine Shults, Samantha Butts, Nicolas Stettler

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in The American journal of clinical nutrition, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 126 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
126citing papers in PubMed, 7 pooled it
38.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

126 citing papers in PubMed, 7 syntheses or guidelines pooled it, 304 citations in OpenAlex.

  1. Beyond the mirror: Exploring the impact of maternal body image attitudes on gestational weight gain and maternal and neonatal outcomes, a systematic review.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
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  12. Gestational Weight Gain and Offspring Bone Mass: Different Associations in Healthy Weight Versus Overweight Women.Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2019
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66 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Brian H WrotniakDivision of Gastroenterology, Hepatology, and Nutrition, The Children's Hospital of Philadelphia, Philadelphia, PA 19104-4399, USA. wrotniak@email.chop.edu
Justine Shults
Samantha Butts
Nicolas Stettler
University of Pennsylvania · USChildren's Hospital of Philadelphia · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe earliest determinants of obesity may operate during intrauterine life, and gestational weight gain may influence the intrauterine environment in a way that may affect the risk of overweight in the offspring.

objectiveThe purpose of this study was to examine the association of gestational weight gain with offspring overweight.

designThis was a retrospective cohort study of 10,226 participants from the Collaborative Perinatal Project (1959-1972). Anthropometric and sociodemographic variables were assessed during gestation, at birth, and at age 7 y. The association between gestational weight gain and offspring overweight at 7 y was examined after adjustment for important confounding factors.

resultsThe odds of overweight in offspring at age 7 y increased by 3% for every 1 kg of gestational weight gain (adjusted odds ratio: 1.03; 95% CI: 1.02, 1.05). When gestational weight gain was examined using Institute of Medicine guidelines, the odds of overweight was 48% greater for children of mothers who gained more than the weight gain recommendations than for children of mothers who met the weight gain guidelines (adjusted OR: 1.48; 95% CI: 1.06, 2.06). The association remained significant after additional adjustment for birth weight. The association between gestational weight gain and overweight in the offspring was strongest for women who were underweight before pregnancy (P for interaction < 0.01).

conclusionHelping pregnant women to meet the recommended weight gain during pregnancy may be an important and novel strategy for preventing pediatric obesity.

Indexed as

Weight GainAdolescentAdultBody Mass IndexChildCohort StudiesEthnicityFemaleFetal WeightHumansMaleOdds RatioOverweightPregnancyPrevalenceRacial Groups

Identifiers

PMID18541573
OpenAlexW2121757636

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.