Evidence map›Paper›PMID 18540736›Full record

Trial reportJournal of consulting and clinical psychology2008

A randomized clinical trial of alternative stress management interventions in persons with HIV infection.

Nancy L McCain, D Patricia Gray, R K Elswick, Jolynne W Robins, Inez Tuck, Jeanne M Walter, Sarah M Rausch, Jessica McKinney Ketchum

Open access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of consulting and clinical psychology, 2008. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 11 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 11 syntheses or guidelines pooled it, 176 citations in OpenAlex.

  1. Pooled it
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  10. Aerobic exercise interventions for adults living with HIV/AIDS.The Cochrane database of systematic reviews · 2010
    Pooled it
  11. Tai Chi on psychological well-being: systematic review and meta-analysis.BMC complementary and alternative medicine · 2010
    Pooled it
  12. Trial
  13. Trial
  14. Trial
  15. Review
  16. Immunomodulatory Effects in Healthy Individuals Following a 4-Week Taoist Qigong Intervention: A Comparative Study.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Article
  17. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nancy L McCainSchool of Nursing, Virginia Commonwealth University, Richmond, VA 23298, USA. nlmccain@vcu.edu
D Patricia Gray
R K Elswick
Jolynne W Robins
Inez Tuck
Jeanne M Walter
Sarah M Rausch
Jessica McKinney Ketchum
Virginia Commonwealth University · US

Funding

X-LINKED HYPOPHOSPHATEMIAM01RR000065 · NCRR · VIRGINIA COMMONWEALTH UNIVERSITY · PI SANYAL, ARUN J · 1985 to 2010
$24.8M
ALTERNATIVE STRESS MANAGEMENT APPROACHES IN HIV DISEASER01AT000331 · NCCIH · VIRGINIA COMMONWEALTH UNIVERSITY · PI MCCAIN, NANCY L · 2000 to 2004
$2.8M
NCCIH NIH HHS 5R01 AT000331NCCIH NIH HHS R01 AT000331NCRR NIH HHS 5M01 RR000065NCRR NIH HHS M01 RR000065
6 · The paper itself

Abstract

Research in psychoneuroimmunology suggests that immunosuppression associated with perceived stress may contribute to disease progression in persons with HIV infection. While stress management interventions may enhance immune function, few alternative approaches have yet been tested. This randomized clinical trial was conducted to test effects of three 10-week stress management approaches--cognitive-behavioral relaxation training (RLXN), focused tai chi training (TCHI), and spiritual growth groups (SPRT)--in comparison to a wait-listed control group (CTRL) among 252 individuals with HIV infection. Using repeated measures mixed modeling, the authors found that in comparison to the CTRL group, (a) both the RLXN and TCHI groups used less emotion-focused coping, and (b) all treatment groups had augmented lymphocyte proliferative function. Despite modest effects of the interventions on psychosocial functioning, robust findings of improved immune function have important clinical implications, particularly for persons with immune-mediated illnesses.

Indexed as

Relaxation TherapySpiritual TherapiesStress, PsychologicalTai JiAdultFemaleHIV InfectionsHumansMaleMiddle AgedPsychoneuroimmunology

Identifiers

PMID18540736
PMCPMC4629773
OpenAlexW2050764828

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.